SCHEMBL8008632

SCHEMBL8008632

CS(=O)(=O)Cc1ccc(C(=O)c2ccc(Cl)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRD5A2 P31213 1/20 0.50
MAPK1 P28482 1/20 0.50
HPGD P15428 1/20 0.49
VNN1 O95497 2/20 0.46
NPC1 O15118 4/20 0.45
RAB9A P51151 2/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
RCE1 Q9Y256 1/20 0.44
ALDH1A1 P00352 3/20 0.43
POLB P06746 2/20 0.43
GAA P10253 2/20 0.43
LMNA P02545 1/20 0.43
AGTR1 P30556 1/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
KDM4E B2RXH2 1/20 0.42
CTDSP1 Q9GZU7 1/20 0.42
ELANE P08246 1/20 0.42
CES2 O00748 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1678837 0.87 L3MBTL1 (0.50) MAPK1L3MBTL1ALDH1A1POLBMEN1
SCHEMBL8491668 0.84 SRD5A2 (0.48) SRD5A2MAPK1HPGDVNN1NPC1
SCHEMBL9772279 0.84 RCE1 (0.56) SRD5A2HPGDNPC1RAB9AL3MBTL1
SCHEMBL8004260 0.82 MAPT (0.49) SRD5A2MAPK1NPC1RAB9ARCE1
SCHEMBL8495528 0.81 MEN1 (0.43) HPGDNPC1RAB9AL3MBTL1RCE1
SCHEMBL8493197 0.80 ALDH1A1 (0.37) HPGDNPC1RAB9AL3MBTL1RCE1
SCHEMBL8495630 0.79 SRD5A2 (0.47) SRD5A2MAPK1HPGDVNN1NPC1
SCHEMBL8494889 0.78 SRD5A2 (0.46) SRD5A2MAPK1HPGDVNN1NPC1
SCHEMBL28399335 0.77 ALDH1A1 (0.65) SRD5A2MAPK1HPGDVNN1NPC1
SCHEMBL402122 0.77 KMT2A (0.59) SRD5A2NPC1L3MBTL1RCE1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6077866-A EXHIBIT POWERFUL INSECTICIDAL ACTION, ESPECIALLY AGAINST LEPIDOPTERA, COLEOPTERA AND SOIL INSECTS NIHON BAYER AGROCHEM K.K. (JP) 2000-06-20 US disclosed
EP-0742202-B1 Benzophenone hydrazone derivatives as insecticides BAYER AGROCHEM KK (JP) 1999-12-01 EP disclosed
EP-0766666-B1 BENZYLSULFIDE DERIVATIVE, PROCESS FOR ITS PRODUCTION AND PESTICIDE KUMIAI CHEMICAL INDUSTRY CO (JP) 1999-03-17 EP disclosed
US-5728699-A Benzylsulfide derivative, process for its production and pesticide KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1998-03-17 US disclosed
EP-0766666-A1 BENZYLSULFIDE DERIVATIVE, PROCESS FOR ITS PRODUCTION AND PESTICIDE KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1997-04-09 EP disclosed
EP-0742202-A2 Benzophenone hydrazone derivatives as insecticides NIHON BAYER AGROCHEM K.K. (JP) 1996-11-13 EP disclosed
WO-1996033168-A1 BENZYLSULFIDE DERIVATIVE, PROCESS FOR ITS PRODUCTION AND PESTICIDE KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1996-10-24 WO disclosed