Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CDK4 | P11802 | 7/20 | 0.49 |
| ▸ | CCND1 | P24385 | 6/20 | 0.49 |
| ▸ | CDK2 | P24941 | 5/20 | 0.49 |
| ▸ | CCNE2 | O96020 | 4/20 | 0.49 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAPDH | P04406 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | KIT | P10721 | 1/20 | 0.44 |
| ▸ | ALPL | P05186 | 1/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.43 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5216372 | 0.81 | CDK4 (0.50) | KMT2AMEN1CDK4CCND1CDK2 | |
| SCHEMBL5218883 | 0.80 | PDPK1 (0.45) | CDK2DYRK1B | |
| SCHEMBL19923002 | 0.80 | ALDH1A1 (0.51) | HTTMAPK10SMN1; SMN2KDM4EMAPT | |
| SCHEMBL12567890 | 0.80 | ALDH1A1 (0.55) | HTTMAPK10SMN1; SMN2KDM4EMAPT | |
| SCHEMBL22784037 | 0.74 | CCNE2 (0.46) | KMT2AMEN1CDK4CCND1CDK2 | |
| SCHEMBL8020401 | 0.73 | MAPT (0.67) | KMT2AMEN1CDK4CCND1CDK2 | |
| SCHEMBL22774907 | 0.72 | CCNE2 (0.45) | KMT2AMEN1CDK4CCND1CDK2 | |
| SCHEMBL17279838 | 0.72 | ALDH1A1 (0.46) | CDK2MAPK10SMN1; SMN2KDM4EMAPT | |
| SCHEMBL8890557 | 0.72 | SMN1; SMN2 (0.53) | KMT2AMEN1CDK4CCND1CDK2 | |
| SCHEMBL28102260 | 0.72 | MAPT (0.56) | KMT2AMEN1CDK4CCND1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000019994-A1 | ESTROGEN RECEPTOR LIGANDS | BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2000-04-13 | — | — | WO | disclosed |