Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 8/20 | 0.67 |
| ▸ | DRD2 | P14416 | 6/20 | 0.67 |
| ▸ | DRD3 | P35462 | 5/20 | 0.67 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | HTR1A | P08908 | 1/20 | 0.58 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.58 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.58 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11701339 | 0.88 | DRD4 (0.77) | DRD4DRD2DRD3MEN1KMT2A | |
| SCHEMBL23067912 | 0.86 | DRD2 (0.77) | DRD4DRD2DRD3MEN1KMT2A | |
| SCHEMBL2909008 | 0.83 | HTR1A (0.74) | DRD4DRD2DRD3MEN1KMT2A | |
| Bromide SCHEMBL9548125 | 0.82 | HTR1A (0.72) | DRD4DRD2DRD3MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8159235 | 0.82 | HTR1A (0.72) | DRD4DRD2DRD3MEN1KMT2A | |
| SCHEMBL9271263 | 0.82 | HRH1 (0.69) | DRD4DRD2DRD3MEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL2906266 | 0.82 | HTR1A (0.72) | DRD4DRD2DRD3MEN1KMT2A | |
| SCHEMBL11148020 | 0.81 | HTR1A (0.73) | DRD4DRD2DRD3MEN1KMT2A | |
| SCHEMBL11348527 | 0.81 | DRD2 (0.66) | DRD4DRD2DRD3MEN1KMT2A | |
| SCHEMBL11284208 | 0.80 | DRD4 (0.67) | DRD4DRD2DRD3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009116069-A2 | PROCESS FOR PREPARATION OF 1-(9H-CARBAZOL-4-YLOXY)-3-[[2-(2- METHOXYPHENOXY) ETHYL] AMINO]-2-PROPANOL | IPCA LABORATORIES LIMITED (IN) | 2009-09-24 | — | — | WO | disclosed |