Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | KDM4A | O75164 | 14/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.38 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 13/20 | 0.35 |
| ▸ | KDM5A | P29375 | 2/20 | 0.35 |
| ▸ | PHF8 | Q9UPP1 | 2/20 | 0.35 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.35 |
| ▸ | KDM7A | Q6ZMT4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11859986 | 0.77 | KDM5A (0.58) | KDM4AKDM4CKDM5APHF8KDM2A | |
| SCHEMBL8968240 | 0.75 | LMNA (0.39) | ALOX5KDM4AKDM4CKDM5APHF8 | |
| SCHEMBL30966029 | 0.73 | LMNA (0.37) | ALOX5KDM4AKDM4CKDM5APHF8 | |
| SCHEMBL22081042 | 0.72 | — | — | |
| SCHEMBL22031943 | 0.72 | — | — | |
| SCHEMBL22081688 | 0.70 | — | — | |
| SCHEMBL12179743 | 0.70 | — | — | |
| SCHEMBL14981963 | 0.69 | KDM4A (0.62) | KDM4AHIF1ATET2DOHHKDM4C | |
| SCHEMBL18951929 | 0.68 | KDM4A (0.66) | KDM4AHIF1ATET2DOHHKDM4C | |
| SCHEMBL18970370 | 0.68 | KDM4C (0.66) | KDM4AKDM4CKDM5APHF8KDM2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6056939-A | Self-assembling heteropolymetallic chelates as imaging agents and radiopharmaceuticals | BRACCO IMAGING S.P.A. (IT) | 2000-05-02 | — | — | US | disclosed |