SCHEMBL8968240

SCHEMBL8968240

NCCC(=O)N(O)CC(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.39
BLM P54132 3/20 0.39
THRB P10828 2/20 0.39
KMT2A Q03164 2/20 0.39
NPSR1 Q6W5P4 2/20 0.39
TSHR P16473 2/20 0.39
GABRR3 A8MPY1 1/20 0.39
GABRP O00591 1/20 0.39
GABRD O14764 1/20 0.39
HDAC3 O15379 1/20 0.39
GABBR2 O75899 1/20 0.39
CYP1A2 P05177 1/20 0.39
GABRA1 P14867 1/20 0.39
GABRB1 P18505 1/20 0.39
GABRG2 P18507 1/20 0.39
GABRR1 P24046 1/20 0.39
GABRB3 P28472 1/20 0.39
GABRR2 P28476 1/20 0.39
SLC6A1 P30531 1/20 0.39
GABRA5 P31644 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30966029 0.98 LMNA (0.37) LMNABLMTHRBKMT2ANPSR1
SCHEMBL8968167 0.80 GLRA1 (0.45) LMNABLMTHRBKMT2ANPSR1
SCHEMBL8604784 0.78 LMNA (0.40) LMNABLMTHRBKMT2ANPSR1
SCHEMBL8008937 0.75 ALOX5 (0.38) LMNAKDM4AKDM4CPHF8KDM2A
SCHEMBL28427604 0.74 PHF8 (0.41) LMNABLMTHRBKMT2ANPSR1
SCHEMBL9836344 0.71 KDM5A (0.59) KMT2ATSHRHDAC11ALOX15MEN1
SCHEMBL9835679 0.70 KDM5A (0.60) KMT2ATSHRHDAC11ALOX15MEN1
SCHEMBL7049362 0.70 KDM4C (0.39) KDM4AKDM4CPHF8KDM2AKDM5A
SCHEMBL10690717 0.70 KDM5A (0.60) KMT2ATSHRHDAC11ALOX15MEN1
SCHEMBL28733267 0.70 TDP1 (0.34) LMNABLMTHRBKMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0695289-A1 HYDROXAMIC ACIDS AND HYDROXAMIC ACID ETHERS AND THEIR USE AS COMPLEXING AGENTS BASF AKTIENGESELLSCHAFT (DE) 1996-02-07 EP disclosed
WO-1994024096-A1 HYDROXAMIC ACIDS AND HYDROXAMIC ACID ETHERS AND THEIR USE AS COMPLEXING AGENTS BASF AKTIENGESELLSCHAFT (DE) 1994-10-27 WO disclosed