Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trolamine SCHEMBL7754018 | 0.82 | MAPT (0.35) | MAPTCYP2C9ALDH1A1CYP2D6 | |
| Dimethylaminoethanol SCHEMBL28282228 | 0.78 | MAPT (0.75) | MAPTTDP1CYP2C9CYP2C19ALDH1A1 | |
| Dimethylaminoethanol SCHEMBL20677258 | 0.78 | MAPT (0.75) | MAPTTDP1CYP2C9CYP2C19ALDH1A1 | |
| Ethylene Glycol SCHEMBL16685532 | 0.78 | ALDH1A1 (0.41) | ALDH1A1CYP2D6 | |
| Dimethylaminoethanol SCHEMBL16756236 | 0.78 | — | — | |
| Dimethylaminoethanol SCHEMBL5945 | 0.78 | — | — | |
| Dimethylaminoethanol SCHEMBL13169672 | 0.78 | — | — | |
| Dimethylaminoethanol SCHEMBL2149038 | 0.78 | MAPT (1.00) | MAPTTDP1HTR1ADRD2HTR2A | |
| Deanol SCHEMBL7163532 | 0.77 | MAPT (0.63) | MAPTTDP1HTR1ADRD2HTR2A | |
| SCHEMBL2059819 | 0.76 | CYP1A2 (0.45) | MAPTCYP2C9ALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0830336-A4 | PROCESS FOR THE PREPARATION OF TERTIARY AMINOCARBONATES AND AMINOETHERS | OSI SPECIALTIES INC (US) | 2000-04-05 | — | — | EP | disclosed |
| EP-0830336-A1 | PROCESS FOR THE PREPARATION OF TERTIARY AMINOCARBONATES AND AMINOETHERS | OSi Specialties, Inc. (US) | 1998-03-25 | — | — | EP | disclosed |
| WO-1996040613-A1 | PROCESS FOR THE PREPARATION OF TERTIARY AMINOCARBONATES AND AMINOETHERS | OSI SPECIALTIES, INC. (US) | 1996-12-19 | — | — | WO | disclosed |