Trolamine

Trolamine

SCHEMBL7754018

CC(C)(O)CN.OCCN(CCO)CCO

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.35
ALDH1A1 P00352 2/20 0.34
HPGD P15428 2/20 0.34
MAPK1 P28482 2/20 0.34
KDM4E B2RXH2 1/20 0.34
HTT P42858 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
CYP2D6 P10635 1/20 0.32
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
HIF1A Q16665 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trolamine SCHEMBL11034525 0.91 KDM4E (0.31) MAPTALDH1A1HPGDMAPK1KDM4E
SCHEMBL2059819 0.88 CYP1A2 (0.45) MAPTALDH1A1HPGDMAPK1KDM4E
SCHEMBL8994199 0.84 LMNA (0.38) ALDH1A1SMN1; SMN2HSD17B10
Dimethylaminoethanol SCHEMBL8008957 0.82 MAPT (0.60) MAPTALDH1A1CYP2D6CYP2C9
Trolamine SCHEMBL28164611 0.81 MAPT (0.36) MAPTALDH1A1HPGDMAPK1KDM4E
Ethylene Glycol SCHEMBL16685532 0.80 ALDH1A1 (0.41) ALDH1A1KDM4ECYP2D6
SCHEMBL11550981 0.79 HTR1A (0.32) ALDH1A1KDM4ECYP2D6HIF1AHSD17B10
Monoethanolamine SCHEMBL25238120 0.77 ALDH1A1 (0.53) ALDH1A1KDM4ECYP2D6
Monoethanolamine SCHEMBL28263380 0.77 ALDH1A1 (0.53) ALDH1A1KDM4ECYP2D6
Trolamine SCHEMBL2889481 0.77 HPGD (0.34) MAPTALDH1A1HPGDMAPK1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107383313-A A kind of filled-type rigid composite material based on vamp leftover pieces and preparation method thereof 河北科技大学 2017-11-24 CN claimed
US-5077348-A Copolymer of acrylates, acrylated polyether, unsaturated acids and vinyl monomers blended with aqueous amine formaldehyde condensate TOYO INK MANUFACTURING CO., LTD. (JP) 1991-12-31 US claimed
CN-107383313-A A kind of filled-type rigid composite material based on vamp leftover pieces and preparation method thereof 河北科技大学 2017-11-24 CN disclosed
EP-0634696-B2 Chemically amplified resist composition JAPAN SYNTHETIC RUBBER CO LTD (JP) 2001-01-31 EP disclosed
CN-1026569-C Special smooth-skin polyurethane foam plastic for oil seal TIANJIN POLYURETHANE PLASTICS (CN) 1994-11-16 CN disclosed