Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | LDHA | P00338 | 3/20 | 0.45 |
| ▸ | LDHB | P07195 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27471554 | 0.80 | TP53 (0.49) | TP53RECQLMAPK1LDHALDHB | |
| SCHEMBL11811500 | 0.76 | MAP1LC3B (0.47) | MAPK1LDHASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL24923794 | 0.73 | TP53 (0.49) | TP53RECQLMAPK1LDHALDHB | |
| SCHEMBL7561032 | 0.71 | TP53 (0.56) | TP53RECQLMAPK1LDHALDHB | |
| SCHEMBL427764 | 0.71 | TP53 (0.85) | TP53RECQLMAPK1LDHALDHB | |
| SCHEMBL7568239 | 0.71 | TP53 (0.56) | TP53RECQLMAPK1LDHALDHB | |
| SCHEMBL29582956 | 0.69 | TP53 (0.57) | TP53RECQLMAPK1LDHALDHB | |
| SCHEMBL21821946 | 0.69 | TP53 (0.57) | TP53RECQLMAPK1LDHALDHB | |
| SCHEMBL6797464 | 0.68 | TP53 (1.00) | TP53RECQLMAPK1LDHALDHB | |
| SCHEMBL7681186 | 0.68 | TP53 (0.48) | TP53RECQLMAPK1LDHALDHB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0976707-A1 | CYCLOALKYL BENZYL ETHER COMPOUNDS | Nissan Chemical Industries, Ltd. (JP) | 2000-02-02 | — | — | EP | disclosed |