Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 3/20 | 0.47 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.42 |
| ▸ | KLK1 | P06870 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | KIT | P10721 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | VNN1 | O95497 | 2/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | BCR | P11274 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1495422 | 0.92 | WDR5 (0.48) | WDR5KLKB1KLK1HDAC1KIT | |
| SCHEMBL1495553 | 0.90 | WDR5 (0.47) | WDR5KLKB1KLK1GRM5NAMPT | |
| SCHEMBL1495829 | 0.89 | WDR5 (0.45) | WDR5KLKB1KLK1GRM5NAMPT | |
| SCHEMBL1495705 | 0.84 | CA1 (0.43) | WDR5KLKB1KLK1GRM5NAMPT | |
| SCHEMBL1495425 | 0.84 | P2RX3 (0.48) | WDR5P2RX3P2RX2 | |
| SCHEMBL12757573 | 0.84 | WDR5 (0.49) | WDR5HDAC1P2RX3P2RX2 | |
| SCHEMBL1495450 | 0.83 | AKR1C3 (0.46) | KLKB1KLK1HDAC1KITHPGD | |
| SCHEMBL12757575 | 0.82 | WDR5 (0.45) | WDR5HDAC1PIK3CAP2RX3P2RX2 | |
| SCHEMBL1495494 | 0.82 | AKR1C3 (0.45) | KLKB1KLK1GRM5HDAC1KIT | |
| SCHEMBL1495395 | 0.81 | AKR1C3 (0.44) | KLKB1KLK1GRM5HDAC1KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009110985-A2 | AMIDE COMPOUNDS, COMPOSITIONS AND USES THEREOF | RENOVIS, INC. (US) | 2009-09-11 | — | — | WO | disclosed |