SCHEMBL8009129

SCHEMBL8009129

CCCCCCCCO[C@H]1O[C@H](CO[C@@H]2O[C@H](C)[C@@H](O)[C@H](O)[C@@H]2O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]2NC(C)=O)[C@@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.66
LGALS8 O00214 2/20 0.57
LGALS3 P17931 2/20 0.57
LGALS4 P56470 2/20 0.57
BMP2 P12643 2/20 0.46
VEGFA P15692 2/20 0.46
CXCL12 P48061 2/20 0.46
SHH Q15465 2/20 0.46
CD209 Q9NNX6 2/20 0.46
SELP P16109 3/20 0.46
IFNG P01579 1/20 0.46
PF4 P02776 1/20 0.46
CCL2 P13500 1/20 0.46
BMP6 P22004 1/20 0.46
CCL11 P51671 1/20 0.46
WNT3A P56704 1/20 0.46
SELPLG Q14242 1/20 0.46
SELL P14151 3/20 0.44
CD69 Q07108 1/20 0.44
ALDH1A1 P00352 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8009126 1.00 MAPK1 (0.66) MAPK1LGALS8LGALS3LGALS4BMP2
SCHEMBL8744540 0.96 MAPK1 (0.72) MAPK1LGALS8LGALS3LGALS4BMP2
SCHEMBL8744533 0.96 MAPK1 (0.72) MAPK1LGALS8LGALS3LGALS4BMP2
SCHEMBL8744666 0.91 LGALS8 (0.55) MAPK1LGALS8LGALS3LGALS4CD209
SCHEMBL8744635 0.91 LGALS8 (0.55) MAPK1LGALS8LGALS3LGALS4CD209
SCHEMBL8744609 0.90 MAPK1 (0.68) MAPK1LGALS8LGALS3LGALS4BMP2
SCHEMBL8744620 0.90 MAPK1 (0.68) MAPK1LGALS8LGALS3LGALS4BMP2
SCHEMBL8744664 0.86 CD69 (0.51) MAPK1LGALS8LGALS3LGALS4CD209
SCHEMBL8744658 0.86 CD69 (0.51) MAPK1LGALS8LGALS3LGALS4CD209
SCHEMBL8744598 0.86 CD69 (0.51) MAPK1LGALS8LGALS3LGALS4CD209

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6015701-A FOR GENETICALLY ENGINEERED PRODUCTION OF ENZYME UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2000-01-18 US disclosed
EP-0602237-B1 N-ACETYLGLUCOSAMINYLTRANSFERASE V CODING SEQUENCES UNIV GEORGIA RES FOUND (US) 1998-11-25 EP disclosed
US-5602003-A ISOLATED NUCLEOTIDE SEQUENCE WHICH CODES FOR ACTIVE POLYPEPTIDE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION (US) 1997-02-11 US disclosed