Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.68 |
| ▸ | LGALS8 | O00214 | 2/20 | 0.57 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.57 |
| ▸ | LGALS4 | P56470 | 2/20 | 0.57 |
| ▸ | BMP2 | P12643 | 2/20 | 0.47 |
| ▸ | VEGFA | P15692 | 2/20 | 0.47 |
| ▸ | CXCL12 | P48061 | 2/20 | 0.47 |
| ▸ | SHH | Q15465 | 2/20 | 0.47 |
| ▸ | IFNG | P01579 | 1/20 | 0.47 |
| ▸ | PF4 | P02776 | 1/20 | 0.47 |
| ▸ | CCL2 | P13500 | 1/20 | 0.47 |
| ▸ | SELP | P16109 | 1/20 | 0.47 |
| ▸ | BMP6 | P22004 | 1/20 | 0.47 |
| ▸ | CCL11 | P51671 | 1/20 | 0.47 |
| ▸ | WNT3A | P56704 | 1/20 | 0.47 |
| ▸ | SELPLG | Q14242 | 1/20 | 0.47 |
| ▸ | CD69 | Q07108 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | CD209 | Q9NNX6 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8744620 | 1.00 | MAPK1 (0.68) | MAPK1LGALS8LGALS3LGALS4BMP2 | |
| SCHEMBL8744540 | 0.94 | MAPK1 (0.72) | MAPK1LGALS8LGALS3LGALS4BMP2 | |
| SCHEMBL8744533 | 0.94 | MAPK1 (0.72) | MAPK1LGALS8LGALS3LGALS4BMP2 | |
| SCHEMBL8009126 | 0.90 | MAPK1 (0.66) | MAPK1LGALS8LGALS3LGALS4BMP2 | |
| SCHEMBL8009129 | 0.90 | MAPK1 (0.66) | MAPK1LGALS8LGALS3LGALS4BMP2 | |
| SCHEMBL18947591 | 0.87 | MAPK1 (0.76) | MAPK1LGALS8LGALS3LGALS4BMP2 | |
| SCHEMBL18350663 | 0.86 | LGALS8 (0.60) | MAPK1LGALS8LGALS3LGALS4BMP2 | |
| SCHEMBL9463812 | 0.86 | CD69 (0.53) | MAPK1LGALS8LGALS3LGALS4CD69 | |
| SCHEMBL9463806 | 0.86 | CD69 (0.53) | MAPK1LGALS8LGALS3LGALS4CD69 | |
| SCHEMBL8744639 | 0.86 | LGALS8 (0.59) | MAPK1LGALS8LGALS3LGALS4CD69 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0593419-B1 | INHIBITORS FOR GLYCOSAMINOSYL TRANSFERASE-V | ALBERTA RES COUNCIL (CA) | 1997-01-22 | — | — | EP | disclosed |
| US-5206356-A | Therapy and diagnosis of metastatic metabolic states | CHEMBIOMED, LTD. (CA) | 1993-04-27 | — | — | US | disclosed |
| US-5032505-A | Enzyme inhibitors | CHEMBIOMED, LTD. (CA) | 1991-07-16 | — | — | US | disclosed |
| WO-1990005527-A1 | INHIBITORS FOR GLYCOSAMINOSYL TRANSFERASE-V | CHEMBIOMED LTD. (CA) | 1990-05-31 | — | — | WO | disclosed |