Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 8/20 | 0.42 |
| ▸ | CA1 | P00915 | 4/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.41 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.41 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.36 |
| ▸ | DPP4 | P27487 | 5/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 5/20 | 0.36 |
| ▸ | RRM1 | P23921 | 1/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.35 |
| ▸ | REN | P00797 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1486269 | 0.81 | DPP7 (0.59) | DPP7CA1CA2METAP2ANPEP | |
| SCHEMBL5675717 | 0.81 | CA2 (0.44) | DPP7CA1CA2METAP2ANPEP | |
| Hydrochloric Acid SCHEMBL31036347 | 0.80 | DPP7 (0.62) | DPP7CA1CA2SLC15A1SLC1A3 | |
| SCHEMBL8012863 | 0.79 | METAP2 (0.51) | METAP2ANPEPDNPEP | |
| SCHEMBL5675727 | 0.79 | ANPEP (0.53) | DPP7CA1CA2METAP2ANPEP | |
| SCHEMBL8009225 | 0.77 | ANPEP (0.63) | METAP2ANPEPDNPEP | |
| SCHEMBL12141317 | 0.76 | MAPT (0.47) | DPP7CA1CA2METAP2ANPEP | |
| SCHEMBL8280566 | 0.76 | MAPT (0.47) | DPP7CA1CA2METAP2ANPEP | |
| SCHEMBL14974373 | 0.75 | ANPEP (0.41) | DPP7METAP2ANPEPDNPEP | |
| Hydrochloric Acid SCHEMBL7397557 | 0.74 | DPP7 (0.46) | DPP7CA1CA2METAP2ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6117870-A | USEFUL AS THERAPEUTIC DRUG OR PREVENTIVE DRUG OF ARTHRITIS AND RHEUMATISM DUE TO INCREASE OF BONE RESORPTION IN ADDITION TO BONE DISEASES SUCH AS OSTEOPOROSIS, HYPERCALCEMIA, AND PAGET'S DISEASE | FUJIREBIO KABUSHIKI KAISHA (JP) | 2000-09-12 | — | — | US | disclosed |