Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 5/20 | 0.38 |
| ▸ | SRC | P12931 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TLR2 | O60603 | 1/20 | 0.36 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.36 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.36 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.35 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1709967 | 0.82 | CA1 (0.61) | CA1CA2LMNAKMT2AMEN1 | |
| SCHEMBL8699142 | 0.78 | ERN1 (0.49) | CA1CA2KMT2AMEN1TDP1 | |
| SCHEMBL13361454 | 0.78 | ERN1 (0.52) | CA1CA2LMNAKMT2AMEN1 | |
| SCHEMBL5030421 | 0.77 | CA1 (0.43) | CA1CA2LMNAKMT2AMEN1 | |
| SCHEMBL17531796 | 0.74 | CA1 (0.45) | CA1CA2LMNAKMT2AMEN1 | |
| SCHEMBL29661768 | 0.74 | — | — | |
| SCHEMBL97071 | 0.74 | — | — | |
| SCHEMBL14876837 | 0.73 | LMNA (0.50) | CA1CA2LMNAKMT2AMEN1 | |
| SCHEMBL29661859 | 0.73 | LMNA (0.50) | CA1CA2LMNAKMT2AMEN1 | |
| SCHEMBL6898698 | 0.73 | LMNA (0.50) | CA1CA2LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101302172-A | 3,5-diiodosalicylaldehyde Schiff alkali, preparation and use thereof | SUOPING XU (CN) | 2008-11-12 | — | — | CN | claimed |
| CN-103755697-B | 3-[[2-(2-benzyl imino-) thiazole-5-base] methyl] quinoline-2 (1H)-one and preparation and application thereof | HUNAN UNIVERSITY (CN) | 2015-08-05 | — | — | CN | disclosed |
| CN-103755697-A | 3-[[2-(2-benzylamino) thiazole-5-yl]-methyl] quinolone-2(1H)-ketone as well as preparation and application thereof | UNIV HUNAN | 2014-04-30 | — | — | CN | disclosed |
| CN-103396435-A | Dibutyl tin aromatic aldehyde condensed arylamine Schiff base complex as well as preparation method and application thereof | UNIV HENGYANG NORMAL | 2013-11-20 | — | — | CN | disclosed |
| CN-103396436-A | Monobutyltin trichloride substituted salicylidenedimine Schiff base complex as well as preparation method and applications thereof | UNIV HENGYANG NORMAL | 2013-11-20 | — | — | CN | disclosed |
| CN-103360423-A | Benzyltin aromatic aldehyde condensed arylamine Schiff base complex and its preparation method and application thereof | UNIV HENGYANG NORMAL | 2013-10-23 | — | — | CN | disclosed |
| CN-101367891-B | Nitrogen-nitrogen-oxygen nickel complex catalytic system for addition polymerisation of norbornene and its derivant, preparation method and uses thereof | UNIV SOUTH CENTRAL NATIONALITI | 2010-09-08 | — | — | CN | disclosed |
| CN-101367891-A | Nitrogen-nitrogen-oxygen nickel complex catalytic system for addition polymerisation of norbornene and its derivant, preparation method and uses thereof | SOUTH CENTRAL UNIVERSITY FOR N (CN) | 2009-02-18 | — | — | CN | disclosed |
| CN-101302172-A | 3,5-diiodosalicylaldehyde Schiff alkali, preparation and use thereof | SUOPING XU (CN) | 2008-11-12 | — | — | CN | disclosed |
| CN-101161620-A | Method for preparing iodo salicylaldehyde | NANJING QINGSHI TECHNOLOGY DEV (CN) | 2008-04-16 | — | — | CN | disclosed |
| CN-1214011-C | Meta-azacyclic aminobenzoic acid compounds and derivatives thereof as integrin antagonists | SEARLE & CO (US) | 2005-08-10 | — | — | CN | disclosed |
| CN-1291978-A | Meta-azacyclic amino benzoic acid compound and derivatives thereof being integrin antagonists | SEARLE & CO (US) | 2001-04-18 | — | — | CN | disclosed |
| WO-2000015605-A2 | CHIRAL CYANOAMINES AND METHODS OF PREPARATION | TRUSTEES OF BOSTON COLLEGE (US) | 2000-03-23 | — | — | WO | disclosed |
| EP-0952997-A1 | POLYMERIZATION OF OLEFINS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-11-03 | — | — | EP | disclosed |
| WO-1998030609-A1 | POLYMERIZATION OF OLEFINS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-07-16 | — | — | WO | disclosed |
| WO-1998010286-A1 | METHODS FOR PROCESSING CHEMICAL COMPOUNDS HAVING REACTIVE FUNCTIONAL GROUPS | ISIS PHARMACEUTICALS, INC. (US) | 1998-03-12 | — | — | WO | disclosed |
| WO-1998005961-A1 | COMPOUNDS HAVING A PLURALITY OF NITROGENOUS SUBSTITUENTS | ISIS PHARMACEUTICALS, INC. (US) | 1998-02-12 | — | — | WO | disclosed |