Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 5/20 | 0.49 |
| ▸ | TLR2 | O60603 | 1/20 | 0.49 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.49 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.49 |
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL172818 | 0.85 | ERN1 (0.66) | ERN1TLR2TLR1TLR6IGF1R | |
| SCHEMBL29442477 | 0.85 | ERN1 (0.66) | ERN1TLR2TLR1TLR6IGF1R | |
| SCHEMBL8009530 | 0.78 | CA1 (0.44) | ERN1TLR2TLR1TLR6ALDH1A1 | |
| Ethylenediamine SCHEMBL10537022 | 0.78 | ERN1 (0.57) | ERN1TLR2TLR1TLR6IGF1R | |
| Monoethanolamine SCHEMBL28688060 | 0.77 | ERN1 (0.55) | ERN1TLR2TLR1TLR6IGF1R | |
| SCHEMBL27659218 | 0.76 | ERN1 (0.62) | ERN1TLR2TLR1TLR6IGF1R | |
| SCHEMBL20677717 | 0.75 | ERN1 (0.53) | ERN1TLR2TLR1TLR6IGF1R | |
| SCHEMBL27942814 | 0.75 | ERN1 (0.53) | ERN1TLR2TLR1TLR6IGF1R | |
| SCHEMBL29922833 | 0.74 | ALDH1A1 (0.50) | ERN1TLR2TLR1TLR6ALDH1A1 | |
| SCHEMBL181586 | 0.74 | ALDH1A1 (0.50) | ERN1TLR2TLR1TLR6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998008813-A1 | COMBINATORIAL PROCESS FOR PREPARING SUBSTITUTED PYRROLIDINE LIBRARIES | ELI LILLY AND COMPANY (US) | 1998-03-05 | — | — | WO | disclosed |