SCHEMBL8009563

SCHEMBL8009563

CC(=Cc1ccc([N+](=O)[O-])cc1)C(N)=O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.60
KDM4E B2RXH2 2/20 0.60
ALDH1A1 P00352 2/20 0.60
SMN1; SMN2 Q16637 1/20 0.60
FBP1 P09467 2/20 0.53
NOS1 P29475 2/20 0.50
TSHR P16473 1/20 0.50
MAPK1 P28482 1/20 0.50
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
GRIN2D O15399 2/20 0.49
GRIN3B O60391 2/20 0.49
GRIN1 Q05586 2/20 0.49
GRIN2A Q12879 2/20 0.49
GRIN2B Q13224 2/20 0.49
GRIN2C Q14957 2/20 0.49
GRIN3A Q8TCU5 2/20 0.49
LMNA P02545 1/20 0.46
GAA P10253 1/20 0.46
APP P05067 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9065473 1.00 MAPT (0.60) MAPTKDM4EALDH1A1SMN1; SMN2FBP1
SCHEMBL28313969 0.86 FBP1 (0.56) MAPTKDM4EALDH1A1SMN1; SMN2FBP1
SCHEMBL52681 0.84 AKR1C3 (0.58) MAPTKDM4EALDH1A1SMN1; SMN2FBP1
SCHEMBL481147 0.84 AKR1C3 (0.58) MAPTKDM4EALDH1A1SMN1; SMN2FBP1
SCHEMBL17009045 0.84 AKR1C3 (0.58) MAPTKDM4EALDH1A1SMN1; SMN2FBP1
SCHEMBL7253472 0.83 ALDH1A1 (0.57) MAPTKDM4EALDH1A1SMN1; SMN2FBP1
SCHEMBL7250782 0.83 ALDH1A1 (0.57) MAPTKDM4EALDH1A1SMN1; SMN2FBP1
SCHEMBL5830527 0.83 AKR1C3 (0.52) MAPTKDM4EALDH1A1SMN1; SMN2MEN1
SCHEMBL5830531 0.83 AKR1C3 (0.52) MAPTKDM4EALDH1A1SMN1; SMN2MEN1
SCHEMBL11101235 0.83 FBP1 (0.62) MAPTKDM4EALDH1A1SMN1; SMN2FBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103459437-B Polymerizable monomer, polymeric compound, charge control agent containing the polymeric compound, and developer bearing member and toner which contain the charge control agent CANON KK 2015-06-03 CN disclosed
CN-103459437-A Polymerizable monomer, polymeric compound, charge control agent containing the polymeric compound, and developer bearing member and toner which contain the charge control agent CANON KK 2013-12-18 CN disclosed
WO-2000034804-A1 HIGH REFRACTIVE INDEX HYDROGEL COMPOSITIONS FOR OPHTHALMIC IMPLANTS BAUSCH & LOMB SURGICAL, INC. (US) 2000-06-15 WO disclosed
US-5571642-A LIGHT SENSITIVE ELEMENTS WITH CHEMICAL RESISTANCE FUJI PHOTO FILM CO., LTD. (JP) 1996-11-05 US disclosed