Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.69 |
| ▸ | CA2 | P00918 | 4/20 | 0.69 |
| ▸ | CA12 | O43570 | 3/20 | 0.69 |
| ▸ | CA9 | Q16790 | 3/20 | 0.69 |
| ▸ | MMP1 | P03956 | 1/20 | 0.67 |
| ▸ | MMP2 | P08253 | 1/20 | 0.67 |
| ▸ | MMP9 | P14780 | 1/20 | 0.67 |
| ▸ | MMP8 | P22894 | 1/20 | 0.67 |
| ▸ | MMP13 | P45452 | 1/20 | 0.67 |
| ▸ | PKM | P14618 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | F2 | P00734 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acedapsone SCHEMBL152710 | 0.85 | PKM (0.85) | CA1CA2CA12CA9MMP1 | |
| SCHEMBL1102016 | 0.83 | CA1 (0.69) | CA1CA2CA12CA9MMP1 | |
| Acedapsone SCHEMBL22518385 | 0.83 | PKM (0.82) | CA1CA2CA12CA9MMP1 | |
| Acedapsone SCHEMBL28716352 | 0.83 | PKM (0.82) | CA1CA2CA12CA9MMP1 | |
| SCHEMBL756792 | 0.83 | CA1 (0.69) | CA1CA2CA12CA9MMP1 | |
| SCHEMBL861674 | 0.82 | SMN1; SMN2 (0.84) | CA1CA2CA12CA9POLB | |
| SCHEMBL12916667 | 0.82 | CA1 (0.67) | CA1CA2CA12CA9MMP1 | |
| SCHEMBL8389551 | 0.82 | CA1 (0.67) | CA1CA2CA12CA9MMP1 | |
| SCHEMBL11883912 | 0.82 | POLB (0.69) | CA1CA2CA12CA9MMP1 | |
| SCHEMBL58191 | 0.82 | CA1 (0.67) | CA1CA2CA12CA9MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6107299-A | INSECTICIDES; MITICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 2000-08-22 | — | — | US | disclosed |