SCHEMBL58191

SCHEMBL58191

CC(=O)Nc1ccc(S(=O)(=O)Cl)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.67
CA2 P00918 3/20 0.67
CA12 O43570 2/20 0.67
CA9 Q16790 2/20 0.67
MMP1 P03956 1/20 0.65
MMP2 P08253 1/20 0.65
MMP9 P14780 1/20 0.65
MMP8 P22894 1/20 0.65
MMP13 P45452 1/20 0.65
PKM P14618 2/20 0.62
POLB P06746 2/20 0.61
CYP2C19 P33261 1/20 0.61
KMT2A Q03164 3/20 0.59
ALDH1A1 P00352 2/20 0.59
MAPT P10636 1/20 0.59
L3MBTL1 Q9Y468 2/20 0.57
HTT P42858 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.57
KDM4E B2RXH2 1/20 0.57
F2 P00734 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28865482 1.00 CA1 (0.67) CA1CA2CA12CA9MMP1
Benzene SCHEMBL7868495 0.96 CA1 (0.62) CA1CA2CA12CA9MMP1
SCHEMBL7530654 0.93 PKM (0.75) CA1CA2CA12CA9MMP1
SCHEMBL31500692 0.90 MMP2 (0.59) CA1CA2CA12CA9MMP1
Pyridine SCHEMBL8669427 0.88 GAA (0.57) CA1CA2CA12CA9MMP1
Sulfanilamide SCHEMBL11380883 0.86 CA1 (0.73) CA1CA2CA12CA9PKM
SCHEMBL29141323 0.85 CA1 (0.50) CA1CA2CA12CA9MMP1
SCHEMBL28863414 0.84 LMNA (0.55) CA1CA2CA12CA9MMP1
SCHEMBL949134 0.84 CA2 (0.53) CA1CA2CA12CA9MMP1
Acedapsone SCHEMBL152710 0.83 PKM (0.85) CA1CA2CA12CA9MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2453 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119504511-A Method for preparing high-quality acetamido benzene sulfonyl chloride 湖南吴赣药业有限公司 2025-02-25 CN claimed
CN-119019297-A Halogen modified hapten for enhancing antibody affinity as well as preparation method and application thereof 中国农业大学 2024-11-26 CN claimed
WO-2024228999-A2 MICRO-MESOPOROUS CARBON AND METHODS OF MAKING AND USING SAME WILLIAM MARSH RICE UNIVERSITY (US) 2024-11-07 WO claimed
WO-2024205303-A1 NOVEL AMIDE-BASED COMPOUND AND COMPOSITION COMPRISING SAME (주)아모레퍼시픽 2024-10-03 WO claimed
CN-118515773-A Sulfonamide monoclonal antibody, detection test strip and application thereof 北京纳百生物科技有限公司 2024-08-20 CN claimed
CN-108191742-B 4-acetamidobenzenesulfonyl-substituted 3, 5-diarylmethylene-4-piperidone compound and preparation method thereof 滨州医学院 2023-06-27 CN claimed
CN-115850199-A Preparation method of high-purity sulfisoxazole sodium 天和药业股份有限公司 2023-03-28 CN claimed
CN-115677599-A Method for preparing 4- (p-acetamido benzene sulfonamide) -6-methoxy pyrimidine 沈阳化工研究院有限公司 2023-02-03 CN claimed
CN-110028457-B Isotope labeled sulfabromodimethyl pyrimidine and synthesis method thereof 深圳出入境检验检疫局食品检验检疫技术中心 2023-01-20 CN claimed
CN-115219621-A Method for quantitatively analyzing p-acetamido-benzenesulfonyl chloride based on derivatization method 济南同路医药科技发展有限公司 2022-10-21 CN claimed
CN-1569618-A Process for preparing hydrogen sulfide TANG PEIKUN (CN) 2005-01-26 CN claimed
EP-1118644-A2 Hot melt printing ink Siegwerk Druckfarben GmbH & Co. KG (DE) 2001-07-25 EP claimed
US-5395936-A Antibacterial agents MANZO RUBEN H (AR) 1995-03-07 US claimed
EP-0315638-B1 USE OF SULFONAMIDE DERIVATIVES FOR THE PREPARATION OF AN ANTIVIRAL MEDICAMENT Chemische Fabrik Stockhausen GmbH (DE) 1991-01-09 EP claimed
EP-0315638-A1 Use of sulfonamide derivatives for the preparation of an antiviral medicament. STOCKHAUSEN CHEM FAB GMBH (DE) 1989-05-17 EP claimed
WO-1988000828-A1 ANTIVIRAL AGENT CHEMISCHE FABRIK STOCKHAUSEN GMBH (DE) 1988-02-11 WO claimed
US-4403072-A Alkoxyethanols as solvents for coupling sulfonyl halides to polymeric amines DYNAPOL (US) 1983-09-06 US claimed
US-4287106-A ACRYLATE MONOMER, DIENE POLYMER CIBA-GEIGY CORPORATION (US) 1981-09-01 US claimed
EP-0021592-A1 Phenylsulphonamide derivatives, a process for their preparation and their use as medicines BEECHAM - WUELFING GmbH & Co. KG (DE) 1981-01-07 EP claimed
US-4107065-A P-ACYLAMINOBENZENESULFONYL CHLORIDE OR BROMIDE COLGATE-PALMOLIVE COMPANY (US) 1978-08-15 US claimed