Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | STAT1 | P42224 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8007061 | 0.80 | MEN1 (0.46) | MEN1KMT2AL3MBTL1ALDH1A1HPGD | |
| SCHEMBL8009220 | 0.72 | L3MBTL1 (0.51) | MEN1KMT2AL3MBTL1ALDH1A1HPGD | |
| SCHEMBL9035307 | 0.71 | MEN1 (0.47) | MEN1KMT2AL3MBTL1ALDH1A1HPGD | |
| SCHEMBL6176814 | 0.69 | ALDH1A1 (0.50) | MEN1KMT2AL3MBTL1ALDH1A1HPGD | |
| SCHEMBL6176807 | 0.69 | ALDH1A1 (0.50) | MEN1KMT2AL3MBTL1ALDH1A1HPGD | |
| SCHEMBL27438241 | 0.68 | L3MBTL1 (0.51) | MEN1KMT2AL3MBTL1ALDH1A1HPGD | |
| SCHEMBL27546076 | 0.68 | ALDH1A1 (0.42) | MEN1KMT2AL3MBTL1ALDH1A1GAA | |
| SCHEMBL7998183 | 0.67 | MEN1 (0.48) | MEN1KMT2AL3MBTL1ALDH1A1HPGD | |
| SCHEMBL7998180 | 0.67 | L3MBTL1 (0.48) | MEN1KMT2AL3MBTL1ALDH1A1HPGD | |
| SCHEMBL30453140 | 0.66 | L3MBTL1 (0.60) | MEN1KMT2AL3MBTL1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6165941-A | Substituted 2-phenylpyridines | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-26 | — | — | US | disclosed |
| EP-0708769-A1 | SUBSTITUTED 2-FUSED PHENYLPYRIDINES WITH HERBICIDAL ACTIVITY | BASF AKTIENGESELLSCHAFT (DE) | 1996-05-01 | — | — | EP | disclosed |
| WO-1995002590-A2 | SUBSTITUTED 2-FUSED PHENYLPYRIDINES WITH HERBICIDAL ACTIVITIES | BASF AKTIENGESELLSCHAFT (DE) | 1995-01-26 | — | — | WO | disclosed |