Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALPG | P10696 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
| ▸ | NPY2R | P49146 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25936994 | 0.94 | HTT (0.55) | HTTL3MBTL1CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL20462902 | 0.84 | HTT (0.50) | HTTL3MBTL1CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL25936841 | 0.79 | ACP3 (0.62) | HTTL3MBTL1CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL752826 | 0.79 | HTT (0.66) | HTTL3MBTL1CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL7775603 | 0.77 | HTT (0.46) | HTTL3MBTL1CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL518265 | 0.74 | CYP3A4 (0.68) | HTTL3MBTL1CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL755028 | 0.74 | CYP3A4 (0.68) | HTTL3MBTL1CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL8679316 | 0.74 | CYP3A4 (0.42) | HTTL3MBTL1CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL10824828 | 0.71 | HTT (0.65) | HTTL3MBTL1CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL11700305 | 0.71 | ALDH1A1 (0.60) | HTTL3MBTL1CYP3A4CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0653432-B1 | Process for preparing bis-(diaryl-alkyl)-phosphines and derivatives of this class of substances | CELANESE CHEM EUROPE GMBH (DE) | 2000-02-09 | — | — | EP | disclosed |
| US-5600006-A | Bis(diarylalkyl)phosphines | HOECHST A.G. (DE) | 1997-02-04 | — | — | US | disclosed |
| EP-0653432-A1 | Process for preparing bis-(diaryl-alkyl)-phosphines and novel derivatives of this class of substances | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-05-17 | — | — | EP | disclosed |