Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5599296 | 0.85 | HCAR2 (0.65) | HCAR2HCAR3 | |
| SCHEMBL3211090 | 0.81 | CYP4F2 (0.41) | CYP4F2CYP4A11MAPTHCAR2LMNA | |
| SCHEMBL3204772 | 0.79 | CYP4F2 (0.39) | CYP4F2CYP4A11MAPTHCAR2LMNA | |
| SCHEMBL5107095 | 0.79 | PDE3B (0.40) | CYP4F2CYP4A11MAPTHCAR2LMNA | |
| SCHEMBL27773485 | 0.75 | CYP1A2 (0.44) | CYP4F2CYP4A11HCAR2ALDH1A1KDM4E | |
| SCHEMBL22077971 | 0.74 | — | — | |
| SCHEMBL8010853 | 0.74 | PDE3B (0.39) | CYP4F2CYP4A11MAPTHCAR2ALDH1A1 | |
| SCHEMBL12999481 | 0.73 | ALDH1A1 (0.45) | MAPTALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL24082741 | 0.71 | HCAR2 (0.43) | MAPTHCAR2LMNAALDH1A1KDM4E | |
| SCHEMBL1078882 | 0.71 | CYP4F2 (0.51) | CYP4F2CYP4A11MAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000027394-A1 | ACTIVATORS OF SOLUBLE GUANYLATE CYCLASE | UNIVERSITY COLLEGE LONDON (GB) | 2000-05-18 | — | — | WO | disclosed |