Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 3/20 | 0.32 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.31 |
| ▸ | AKT2 | P31751 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MPI | P34949 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8009896 | 1.00 | CNR1 (0.35) | CNR1CA12CA1CA2CA9 | |
| SCHEMBL8017092 | 0.96 | CNR1 (0.36) | CNR1CA12CA1CA2CA9 | |
| SCHEMBL8017088 | 0.96 | CNR1 (0.36) | CNR1CA12CA1CA2CA9 | |
| SCHEMBL8009405 | 0.93 | MEN1 (0.36) | CNR1CA12CA1CA2CA9 | |
| SCHEMBL8009411 | 0.93 | MEN1 (0.36) | CNR1CA12CA1CA2CA9 | |
| SCHEMBL8009854 | 0.91 | HRH3 (0.37) | CNR1CA12CA1CA2CA9 | |
| SCHEMBL8009849 | 0.91 | HRH3 (0.37) | CNR1CA12CA1CA2CA9 | |
| SCHEMBL8012266 | 0.90 | KMT2A (0.36) | CNR1CA12CA1CA2CA9 | |
| SCHEMBL8012262 | 0.90 | KMT2A (0.36) | CNR1CA12CA1CA2CA9 | |
| SCHEMBL8000714 | 0.90 | CASP1 (0.40) | CNR1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6043254-A | ANTIPROLIFERATIVE AGENT; ENZYME INHIBITOR | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-03-28 | — | — | US | disclosed |