Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 10/20 | 0.51 |
| ▸ | CTSB | P07858 | 2/20 | 0.42 |
| ▸ | CTSV | O60911 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8024921 | 0.85 | CCR3 (0.53) | CCR3CTSBCTSVCTSLCTSS | |
| SCHEMBL8013833 | 0.81 | CCR3 (0.52) | CCR3CTSBCTSVCTSLCTSS | |
| SCHEMBL8009960 | 0.81 | CCR3 (0.53) | CCR3CTSBCTSVCTSLCTSS | |
| SCHEMBL7998209 | 0.81 | CCR3 (0.51) | CCR3CTSBCTSVCTSLCTSS | |
| SCHEMBL7998205 | 0.80 | CCR3 (0.55) | CCR3CTSBCTSVCTSLCTSS | |
| SCHEMBL7998203 | 0.80 | CCR3 (0.55) | CCR3CTSBCTSVCTSLCTSS | |
| SCHEMBL7608481 | 0.79 | CCR3 (0.66) | CCR3CTSBCAPN1CA2 | |
| SCHEMBL8014171 | 0.79 | CCR3 (0.66) | CCR3CTSBCAPN1CA2 | |
| SCHEMBL8009959 | 0.78 | CCR3 (0.55) | CCR3CTSBCTSVCTSLCTSS | |
| SCHEMBL8017638 | 0.78 | CCR3 (0.58) | CCR3CTSBCTSVCTSLCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000027800-A1 | CCR-3 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-05-18 | — | — | WO | claimed |
| WO-2000027800-A1 | CCR-3 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-05-18 | — | — | WO | disclosed |