Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.34 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 5/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | AKT2 | P31751 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8005737 | 0.86 | L3MBTL1 (0.34) | L3MBTL1PRMT6KDM4EALDH1A1LMNA | |
| SCHEMBL7998450 | 0.83 | L3MBTL1 (0.38) | L3MBTL1PRMT6KDM4EALDH1A1LMNA | |
| SCHEMBL8009767 | 0.83 | L3MBTL1 (0.38) | L3MBTL1PRMT6KDM4EALDH1A1LMNA | |
| SCHEMBL8009521 | 0.82 | L3MBTL1 (0.37) | L3MBTL1PRMT6KDM4EALDH1A1LMNA | |
| SCHEMBL7999116 | 0.82 | L3MBTL1 (0.37) | L3MBTL1PRMT6KDM4EALDH1A1LMNA | |
| SCHEMBL10293333 | 0.80 | MAPK14 (0.33) | KDM4ELMNA | |
| SCHEMBL10260261 | 0.80 | NAMPT (0.32) | MAPT | |
| SCHEMBL7998573 | 0.79 | PRMT6 (0.36) | PRMT6ALDH1A1LMNAHCRTR1HCRTR2 | |
| SCHEMBL10293179 | 0.79 | KDM4E (0.31) | KDM4ELMNA | |
| SCHEMBL8000613 | 0.78 | L3MBTL1 (0.32) | L3MBTL1KDM4EALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009134987-A1 | DIFLUOROMETHYL-CONTAINING MACROCYCLIC COMPOUNDS AS HEPATITIS C VIRUS INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2009-11-05 | — | — | WO | disclosed |