Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | MGAM | O43451 | 2/20 | 0.43 |
| ▸ | SI | P14410 | 2/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28918128 | 0.81 | ALDH1A1 (0.42) | HSD11B1ALDH1A1TDP1HSD17B10GAA | |
| SCHEMBL27735343 | 0.78 | ALDH1A1 (0.43) | HSD11B1ALDH1A1TDP1HSD17B10KMT2A | |
| Hydrochloric Acid SCHEMBL4345829 | 0.76 | BRD4 (0.57) | BRD4HSD17B10ADRA1DADRA1AADRA1B | |
| SCHEMBL5698528 | 0.76 | CYP3A4 (0.43) | BRD4ALDH1A1TDP1GAAKMT2A | |
| SCHEMBL5698534 | 0.76 | CYP3A4 (0.43) | BRD4ALDH1A1TDP1GAAKMT2A | |
| SCHEMBL6372007 | 0.75 | HSD11B1 (0.48) | HSD11B1ALDH1A1TDP1HSD17B10GAA | |
| SCHEMBL11046318 | 0.75 | ALDH1A1 (0.55) | HSD11B1ALDH1A1TDP1GAAMGAM | |
| SCHEMBL13587950 | 0.74 | BRD4 (0.56) | BRD4ALDH1A1TDP1HSD17B10ADRA1D | |
| SCHEMBL19171596 | 0.72 | BRD4 (0.54) | BRD4HSD17B10ADRA1DADRA1AADRA1B | |
| SCHEMBL6367092 | 0.72 | TDP1 (0.50) | HSD11B1ALDH1A1TDP1HSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6043254-A | ANTIPROLIFERATIVE AGENT; ENZYME INHIBITOR | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-03-28 | — | — | US | disclosed |
| EP-0083975-B1 | HERBICIDAL SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-11-19 | — | — | EP | disclosed |
| US-4602940-A | HERBICIDES, PLANT GROWTH REGULATOR | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-07-29 | — | — | US | disclosed |
| US-4534790-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-08-13 | — | — | US | disclosed |
| US-4465505-A | Herbicidal sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-08-14 | — | — | US | disclosed |
| EP-0083975-A2 | Herbicidal sulfonamides | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1983-07-20 | — | — | EP | disclosed |