Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TYMP | P19971 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8059160 | 0.93 | CYP2A6 (0.36) | CYP2A6ALDH1A1CYP1A2TSHRHSD17B10 | |
| SCHEMBL8832798 | 0.92 | CYP2A6 (0.35) | CYP2A6ALDH1A1CYP1A2TSHRHSD17B10 | |
| SCHEMBL8056040 | 0.85 | ACP3 (0.35) | CYP2A6ALDH1A1CYP1A2HSD17B10CYP2C19 | |
| SCHEMBL8029700 | 0.84 | CYP2A6 (0.36) | CYP2A6ALDH1A1CYP1A2TSHRHSD17B10 | |
| SCHEMBL8022927 | 0.81 | HPRT1 (0.36) | CYP2A6ALDH1A1TSHRHSD17B10HPGD | |
| SCHEMBL23261750 | 0.79 | TAAR1 (0.36) | CYP2A6ALDH1A1CYP1A2TSHRHSD17B10 | |
| SCHEMBL1423533 | 0.79 | CYP2A6 (0.34) | CYP2A6ALDH1A1CYP1A2TSHRHSD17B10 | |
| SCHEMBL8020132 | 0.78 | CYP2A6 (0.41) | CYP2A6ALDH1A1CYP1A2TSHRHSD17B10 | |
| SCHEMBL6419128 | 0.77 | CYP2A6 (0.38) | CYP2A6ALDH1A1CYP1A2TSHRHSD17B10 | |
| SCHEMBL8023619 | 0.77 | MAPT (0.36) | CYP2A6ALDH1A1CYP1A2TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0653432-B1 | Process for preparing bis-(diaryl-alkyl)-phosphines and derivatives of this class of substances | CELANESE CHEM EUROPE GMBH (DE) | 2000-02-09 | — | — | EP | claimed |
| US-5600006-A | Bis(diarylalkyl)phosphines | HOECHST A.G. (DE) | 1997-02-04 | — | — | US | claimed |
| EP-0653432-A1 | Process for preparing bis-(diaryl-alkyl)-phosphines and novel derivatives of this class of substances | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-05-17 | — | — | EP | claimed |
| EP-0653432-B1 | Process for preparing bis-(diaryl-alkyl)-phosphines and derivatives of this class of substances | CELANESE CHEM EUROPE GMBH (DE) | 2000-02-09 | — | — | EP | disclosed |
| US-5600006-A | Bis(diarylalkyl)phosphines | HOECHST A.G. (DE) | 1997-02-04 | — | — | US | disclosed |
| EP-0653432-A1 | Process for preparing bis-(diaryl-alkyl)-phosphines and novel derivatives of this class of substances | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-05-17 | — | — | EP | disclosed |