Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29447338 | 0.91 | ALDH1A1 (0.39) | CYP2A6TSHRALDH1A1MAPTWDR5 | |
| SCHEMBL3955072 | 0.91 | ALDH1A1 (0.39) | CYP2A6TSHRALDH1A1MAPTWDR5 | |
| SCHEMBL8624095 | 0.90 | MCL1 (0.35) | CYP2A6TSHRCYP1A2ALDH1A1MAPT | |
| SCHEMBL29695262 | 0.89 | ALDH1A1 (0.38) | CYP2A6TSHRALDH1A1MAPTWDR5 | |
| Potassium SCHEMBL29695394 | 0.87 | WDR5 (0.37) | CYP2A6TSHRALDH1A1MAPTWDR5 | |
| SCHEMBL8059160 | 0.87 | CYP2A6 (0.36) | CYP2A6TSHRCYP1A2ALDH1A1MAPT | |
| SCHEMBL8020177 | 0.86 | CYP1A2 (0.35) | CYP2A6TSHRCYP1A2ALDH1A1MAPT | |
| SCHEMBL8020163 | 0.86 | MAPT (0.42) | CYP2A6TSHRCYP1A2ALDH1A1MAPT | |
| SCHEMBL8029934 | 0.85 | CYP1A2 (0.34) | CYP2A6TSHRCYP1A2ALDH1A1HSD11B1 | |
| SCHEMBL8023619 | 0.84 | MAPT (0.36) | CYP2A6TSHRCYP1A2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8113581-A | — | — | None | — | — | JP | disclosed |
| EP-0695756-B1 | Process for the preparation of compounds of the phosphane series as well as their use | CELANESE CHEM EUROPE GMBH (DE) | 2000-03-15 | — | — | EP | disclosed |
| US-5728886-A | Compounds of the phosphine group, their preparation and their use | HOECHST AG (DE) | 1998-03-17 | — | — | US | disclosed |
| JP-H08113581-A | PHOSPHINE COMPOUND, ITS PRODUCTION AND ITS USE | HOECHST AG | 1996-05-07 | — | — | JP | disclosed |
| EP-0695756-A1 | Compounds of the phosphane series, process for their preparation as well as their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-02-07 | — | — | EP | disclosed |