Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | WDR5 | P61964 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8023352 | 0.89 | HPGD (0.35) | HPRT1HPGDAHRALDH1A1CYP2A6 | |
| SCHEMBL8020531 | 0.85 | CYP2A6 (0.37) | HPRT1AHRALDH1A1CYP2A6TSHR | |
| SCHEMBL6423410 | 0.84 | HPRT1 (0.38) | HPRT1HPGDAHRALDH1A1CYP2A6 | |
| SCHEMBL8010374 | 0.81 | CYP2A6 (0.41) | HPGDALDH1A1CYP2A6TSHRHSD17B10 | |
| SCHEMBL8011624 | 0.80 | HSD11B1 (0.38) | HPGDALDH1A1CYP2A6TSHRHSD17B10 | |
| SCHEMBL6424099 | 0.79 | ALDH1A1 (0.35) | HPRT1ALDH1A1CYP2A6TSHRHSD17B10 | |
| SCHEMBL6418430 | 0.78 | HPRT1 (0.38) | HPRT1HPGDAHRALDH1A1CYP2A6 | |
| SCHEMBL8022208 | 0.77 | CES1 (0.37) | HPRT1ALDH1A1CYP2A6TSHRHSD17B10 | |
| SCHEMBL6420832 | 0.76 | CYP2A6 (0.36) | HPRT1AHRALDH1A1CYP2A6TSHR | |
| SCHEMBL29447338 | 0.76 | ALDH1A1 (0.39) | HPRT1ALDH1A1CYP2A6TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0653432-B1 | Process for preparing bis-(diaryl-alkyl)-phosphines and derivatives of this class of substances | CELANESE CHEM EUROPE GMBH (DE) | 2000-02-09 | — | — | EP | claimed |
| US-5600006-A | Bis(diarylalkyl)phosphines | HOECHST A.G. (DE) | 1997-02-04 | — | — | US | claimed |
| US-5600006-A | Bis(diarylalkyl)phosphines | HOECHST A.G. (DE) | 1997-02-04 | — | — | US | disclosed |