Glutathione

SCHEMBL8010444

NC(CCO)C(=O)O.NC(CCSCC(N)C(=O)O)C(=O)O.NC(CS)C(=O)O.N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(=O)O)C(=O)O

nearest known ligand 0.70

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	PTGS1	P23219	1/20	0.70

▸	GSTK1	Q9Y2Q3	1/20	0.70

▸	GLO1	Q04760	3/20	0.49

▸	FNTA	P49354	2/20	0.39

▸	FNTB	P49356	2/20	0.39

▸	PGGT1B	P53609	1/20	0.39

▸	BHMT	Q93088	4/20	0.36

▸	NOD1	Q9Y239	2/20	0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Glutathione SCHEMBL8010455	1.00	PTGS1 (0.70)	PTGS1GSTK1GLO1FNTAFNTB
Glutathione SCHEMBL16513640	0.94	PTGS1 (0.80)	PTGS1GSTK1GLO1FNTAFNTB
Glutathione SCHEMBL16513637	0.94	PTGS1 (0.80)	PTGS1GSTK1GLO1FNTAFNTB
Glutathione SCHEMBL8010450	0.93	PTGS1 (0.62)	PTGS1GSTK1GLO1FNTAFNTB
Glutathione SCHEMBL724436	0.88	PTGS1 (0.85)	PTGS1GSTK1GLO1FNTAFNTB
Glutathione SCHEMBL722499	0.88	PTGS1 (0.85)	PTGS1GSTK1GLO1FNTAFNTB
Glutathione SCHEMBL722500	0.88	PTGS1 (0.85)	PTGS1GSTK1GLO1FNTAFNTB
Glutathione SCHEMBL16513706	0.88	PTGS1 (0.90)	PTGS1GSTK1GLO1FNTAFNTB
Glutathione SCHEMBL16513703	0.88	PTGS1 (0.90)	PTGS1GSTK1GLO1FNTAFNTB
Glutathione SCHEMBL183280	0.86	PTGS1 (0.95)	PTGS1GSTK1GLO1FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-6020139-A	S-adenosyl methionine regulation of metabolic pathways and its use in diagnosis and therapy	ORIDIGM CORPORATION (US)	2000-02-01	—	—	US	disclosed