Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.80 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.80 |
| ▸ | GLO1 | Q04760 | 3/20 | 0.55 |
| ▸ | BHMT | Q93088 | 4/20 | 0.41 |
| ▸ | FNTA | P49354 | 2/20 | 0.40 |
| ▸ | FNTB | P49356 | 2/20 | 0.40 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glutathione SCHEMBL16513640 | 1.00 | PTGS1 (0.80) | PTGS1GSTK1GLO1BHMTFNTA | |
| Glutathione SCHEMBL724436 | 0.94 | PTGS1 (0.85) | PTGS1GSTK1GLO1FNTAFNTB | |
| Glutathione SCHEMBL722500 | 0.94 | PTGS1 (0.85) | PTGS1GSTK1GLO1FNTAFNTB | |
| Glutathione SCHEMBL722499 | 0.94 | PTGS1 (0.85) | PTGS1GSTK1GLO1FNTAFNTB | |
| Glutathione SCHEMBL8010455 | 0.94 | PTGS1 (0.70) | PTGS1GSTK1GLO1BHMTFNTA | |
| Glutathione SCHEMBL8010444 | 0.94 | PTGS1 (0.70) | PTGS1GSTK1GLO1BHMTFNTA | |
| Glutathione SCHEMBL16513349 | 0.90 | PTGS1 (0.85) | PTGS1GSTK1GLO1FNTAFNTB | |
| Glutathione SCHEMBL28175255 | 0.90 | PTGS1 (0.85) | PTGS1GSTK1GLO1FNTAFNTB | |
| Glutathione SCHEMBL28175253 | 0.90 | PTGS1 (0.85) | PTGS1GSTK1GLO1FNTAFNTB | |
| Glutathione SCHEMBL16513351 | 0.90 | PTGS1 (0.85) | PTGS1GSTK1GLO1FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015027116-A1 | DIAGNOSTIC AND PREDICTIVE METABOLITE PATTERNS FOR DISORDERS AFFECTING THE BRAIN AND NERVOUS SYSTEM | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-02-26 | — | — | WO | disclosed |