Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | FBP1 | P09467 | 4/20 | 0.33 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.31 |
| ▸ | HTR1F | P30939 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2720833 | 0.76 | NPSR1 (0.44) | NPSR1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL12451756 | 0.76 | NPSR1 (0.44) | NPSR1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL11829444 | 0.75 | CES1 (0.45) | ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL10045794 | 0.74 | HTR1A (0.35) | NPSR1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL2490061 | 0.73 | POLB (0.44) | NPSR1ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL13247707 | 0.71 | NPSR1 (0.54) | NPSR1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL754010 | 0.69 | NPSR1 (0.47) | NPSR1ALDH1A1KDM4EHPGDMEN1 | |
| SCHEMBL7944992 | 0.68 | NPSR1 (0.50) | NPSR1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL19738005 | 0.68 | NPSR1 (0.50) | NPSR1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL17831838 | 0.67 | NPSR1 (0.48) | NPSR1ALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8518928-B2 | Therapeutic compounds | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2013-08-27 | — | — | US | disclosed |
| US-20120071527-A1 | THERAPEUTIC COMPOUNDS | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071527-A1 | THERAPEUTIC COMPOUNDS | TOP2B, DDB1, TOP1 | NPSR1 2943/4885ALDH1A1 2041/4885KDM4E 1388/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.