Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 4/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.52 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29757946 | 0.82 | ADRA2C (0.71) | ADRA2CL3MBTL1POLBLMNAGAA | |
| SCHEMBL3826083 | 0.82 | ADRA2C (0.71) | ADRA2CL3MBTL1POLBLMNAGAA | |
| SCHEMBL30327328 | 0.80 | ADRA2C (0.64) | ADRA2CL3MBTL1POLBLMNAGAA | |
| SCHEMBL2342698 | 0.80 | ADRA2C (0.64) | ADRA2CL3MBTL1POLBLMNAGAA | |
| SCHEMBL10784048 | 0.80 | ADRA2C (0.68) | ADRA2CL3MBTL1POLBLMNAGAA | |
| SCHEMBL18415528 | 0.80 | ADRA2C (0.68) | ADRA2CL3MBTL1POLBLMNAGAA | |
| SCHEMBL2093001 | 0.79 | ADRA2C (0.62) | ADRA2CL3MBTL1POLBLMNAGAA | |
| SCHEMBL14031178 | 0.78 | L3MBTL1 (0.64) | ADRA2CL3MBTL1POLBLMNAGAA | |
| SCHEMBL18415457 | 0.78 | ADRA2C (0.60) | ADRA2CL3MBTL1POLBLMNAGAA | |
| SCHEMBL10027978 | 0.77 | ADRA2C (0.79) | ADRA2CL3MBTL1POLBLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6022870-A | 4-(HETEROCYCLE-SUBSTITUTED-PHENYL)-1,2,4-TRIAZOL-3-ONES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-02-08 | — | — | US | disclosed |
| EP-0729461-B1 | FUNGICIDAL CYCLIC AMIDES | DU PONT (US) | 1999-11-24 | — | — | EP | disclosed |
| US-5977149-A | Dihydrotriazole compounds and their use for controlling fungal plant diseases | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-11-02 | — | — | US | disclosed |
| US-5747516-A | Dihydroazole compounds and their use for controlling fungal plant diseases | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-05-05 | — | — | US | disclosed |
| EP-0729461-A1 | FUNGICIDAL CYCLIC AMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-09-04 | — | — | EP | disclosed |
| WO-1995014009-A1 | FUNGICIDAL CYCLIC AMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-05-26 | — | — | WO | disclosed |