Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 3/20 | 0.41 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP13 | P45452 | 2/20 | 0.41 |
| ▸ | MMP14 | P50281 | 2/20 | 0.41 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.41 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7862828 | 0.83 | ALDH1A1 (0.43) | ALDH1A1LMNASMN1; SMN2HTTMMP1 | |
| SCHEMBL7857418 | 0.80 | HTT (0.42) | ALDH1A1LMNASMN1; SMN2HTTMAPT | |
| SCHEMBL7857250 | 0.79 | SMN1; SMN2 (0.66) | ALDH1A1LMNASMN1; SMN2HTTMAPT | |
| SCHEMBL20157457 | 0.77 | ALDH1A1 (0.56) | ALDH1A1LMNASMN1; SMN2CYP2C9PKM | |
| SCHEMBL7862803 | 0.77 | HTT (0.39) | ALDH1A1LMNASMN1; SMN2HTTMMP1 | |
| SCHEMBL29746806 | 0.75 | HTT (0.44) | ALDH1A1LMNASMN1; SMN2HTTCYP2C9 | |
| SCHEMBL7865553 | 0.75 | ALDH1A1 (0.51) | ALDH1A1LMNAHTTCYP2C9MAPT | |
| SCHEMBL7863855 | 0.75 | HTT (0.44) | ALDH1A1LMNASMN1; SMN2HTTCYP2C9 | |
| SCHEMBL19622354 | 0.75 | LMNA (0.37) | ALDH1A1LMNASMN1; SMN2HTTCYP2C9 | |
| SCHEMBL14748381 | 0.74 | ALDH1A1 (0.37) | ALDH1A1LMNASMN1; SMN2HTTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2564857-A1 | Boron-containing small molecules as anti-inflammatory agents | Anacor Pharmaceuticals, Inc. (US) | 2013-03-06 | — | — | EP | disclosed |
| WO-2009111676-A2 | BORON-CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS | ANACOR PHARMACEUTICALS, INC (US) | 2009-09-11 | — | — | WO | disclosed |