Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 5/20 | 0.37 |
| ▸ | NTRK2 | Q16620 | 5/20 | 0.37 |
| ▸ | IGF1R | P08069 | 4/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | NTRK3 | Q16288 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8011509 | 0.69 | NR1H2 (0.42) | HPGDBRD4TSHRNR1H2HTR1A | |
| SCHEMBL8525397 | 0.68 | SMN1; SMN2 (0.43) | BRD4NR1H2SLC6A2SLC6A4SMN1; SMN2 | |
| SCHEMBL8484212 | 0.67 | SMN1; SMN2 (0.47) | BRD4TSHRSLC6A2SLC6A4NTRK1 | |
| SCHEMBL8366257 | 0.65 | BRD4 (0.47) | HPGDBRD4NTRK1NTRK2IGF1R | |
| SCHEMBL8593864 | 0.64 | SMN1; SMN2 (0.47) | HPGDTSHRSMN1; SMN2NPC1 | |
| SCHEMBL14505650 | 0.63 | HTT (0.53) | POLBHPGDBRD4TSHRSMN1; SMN2 | |
| SCHEMBL2814012 | 0.63 | MGLL (0.62) | TSHRNR1H2HTR1ASLC6A2SLC6A4 | |
| SCHEMBL19950727 | 0.62 | NR1H2 (0.67) | POLBBRD4TSHRNR1H2HTR1A | |
| SCHEMBL15537943 | 0.62 | BRD4 (0.60) | BRD4SMN1; SMN2RAB9A | |
| SCHEMBL11638396 | 0.61 | NR1H2 (0.74) | TSHRNR1H2HTR1ASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6022870-A | 4-(HETEROCYCLE-SUBSTITUTED-PHENYL)-1,2,4-TRIAZOL-3-ONES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-02-08 | — | — | US | disclosed |
| EP-0729461-B1 | FUNGICIDAL CYCLIC AMIDES | DU PONT (US) | 1999-11-24 | — | — | EP | disclosed |
| US-5977149-A | Dihydrotriazole compounds and their use for controlling fungal plant diseases | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-11-02 | — | — | US | disclosed |
| US-5747516-A | Dihydroazole compounds and their use for controlling fungal plant diseases | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-05-05 | — | — | US | disclosed |
| WO-1995014009-A1 | FUNGICIDAL CYCLIC AMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-05-26 | — | — | WO | disclosed |