Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | PARG | Q86W56 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8484212 | 0.84 | SMN1; SMN2 (0.47) | SMN1; SMN2HTTALDH1A1MEN1KMT2A | |
| SCHEMBL8593864 | 0.78 | SMN1; SMN2 (0.47) | SMN1; SMN2HTTALDH1A1KMT2ALMNA | |
| SCHEMBL8100124 | 0.75 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1MAPTSLC6A4SLC6A2 | |
| SCHEMBL8590523 | 0.69 | KDM4E (0.47) | ALDH1A1MEN1KMT2AGAALMNA | |
| SCHEMBL8099987 | 0.69 | ALDH1A1 (0.40) | SMN1; SMN2HTTALDH1A1MEN1KMT2A | |
| SCHEMBL27560651 | 0.69 | HTT (0.39) | SMN1; SMN2HTTALDH1A1MEN1KMT2A | |
| SCHEMBL8010710 | 0.68 | POLB (0.44) | SMN1; SMN2NR1H2SLC6A4BRD4SLC6A2 | |
| SCHEMBL8155272 | 0.67 | NPC1 (0.34) | SMN1; SMN2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL8481561 | 0.66 | MYC (0.56) | SMN1; SMN2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL1137679 | 0.64 | GAA (0.54) | SMN1; SMN2HTTALDH1A1GAARCE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962436-A | AGRICULTURE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-10-05 | — | — | US | disclosed |
| EP-0810997-A1 | FUNGICIDAL CYCLIC AMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-12-10 | — | — | EP | disclosed |
| WO-1996026191-A1 | FUNGICIDAL CYCLIC AMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-08-29 | — | — | WO | disclosed |