Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 9/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | WDR5 | P61964 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | PDE6D | O43924 | 1/20 | 0.39 |
| ▸ | PDE8A | O60658 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | PDE9A | O76083 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8021169 | 0.73 | CCR3 (0.47) | CCR3MEN1KMT2AMAPTWDR5 | |
| SCHEMBL5580409 | 0.72 | CCR3 (0.49) | CCR3MEN1KMT2AMAPTWDR5 | |
| Hydrochloric Acid SCHEMBL8025141 | 0.71 | CYP19A1 (0.44) | MEN1KMT2AMAPTLMNANPC1 | |
| SCHEMBL8024921 | 0.71 | CCR3 (0.53) | CCR3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7608481 | 0.71 | CCR3 (0.66) | CCR3MEN1KMT2A | |
| SCHEMBL8014171 | 0.71 | CCR3 (0.66) | CCR3MEN1KMT2A | |
| SCHEMBL5580155 | 0.71 | CCR3 (0.48) | CCR3MEN1KMT2AMAPTWDR5 | |
| SCHEMBL5580157 | 0.70 | CCR3 (0.51) | CCR3MEN1KMT2AMAPTWDR5 | |
| SCHEMBL3930225 | 0.69 | CCR3 (0.62) | CCR3ALDH1A1 | |
| SCHEMBL3930227 | 0.69 | CCR3 (0.62) | CCR3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000053172-A1 | CCR-3 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-09-14 | — | — | WO | claimed |
| WO-2000053172-A1 | CCR-3 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-09-14 | — | — | WO | disclosed |