Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28285698 | 1.00 | LMNA (0.48) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL5573408 | 0.91 | TDP1 (0.55) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL28278210 | 0.91 | TDP1 (0.55) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL1417186 | 0.84 | LMNA (0.38) | LMNAL3MBTL1TDP1KDM4ETSHR | |
| SCHEMBL14747625 | 0.84 | LMNA (0.38) | LMNAL3MBTL1TDP1KDM4ETSHR | |
| SCHEMBL12360794 | 0.84 | LMNA (0.38) | LMNAL3MBTL1TDP1KDM4ETSHR | |
| SCHEMBL15694284 | 0.84 | LMNA (0.38) | LMNAL3MBTL1TDP1KDM4ETSHR | |
| SCHEMBL16631615 | 0.84 | LMNA (0.38) | LMNAL3MBTL1TDP1KDM4ETSHR | |
| SCHEMBL21697905 | 0.81 | LMNA (0.43) | LMNAL3MBTL1TDP1KDM4EPDE4A | |
| SCHEMBL25284204 | 0.80 | LMNA (0.48) | LMNAL3MBTL1TDP1KDM4EPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009116067-A2 | NOVEL DERIVATIVES OF ACYL CYANOPYRROLIDINES | SUN PHARMA ADVANCED RESEARCH COMPANY LIMITED (IN) | 2009-09-24 | — | — | WO | disclosed |