Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1417186 | 1.00 | LMNA (0.38) | LMNAL3MBTL1TDP1TSHRMAPK1 | |
| SCHEMBL15694284 | 1.00 | LMNA (0.38) | LMNAL3MBTL1TDP1TSHRMAPK1 | |
| SCHEMBL14747625 | 1.00 | LMNA (0.38) | LMNAL3MBTL1TDP1TSHRMAPK1 | |
| SCHEMBL12360794 | 1.00 | LMNA (0.38) | LMNAL3MBTL1TDP1TSHRMAPK1 | |
| SCHEMBL3229121 | 0.84 | USP2 (0.38) | LMNAL3MBTL1TDP1KDM4E | |
| SCHEMBL28285698 | 0.84 | LMNA (0.48) | LMNAL3MBTL1TDP1TSHRMAPK1 | |
| SCHEMBL8010997 | 0.84 | LMNA (0.48) | LMNAL3MBTL1TDP1TSHRMAPK1 | |
| SCHEMBL28278210 | 0.80 | TDP1 (0.55) | LMNAL3MBTL1TDP1KDM4E | |
| SCHEMBL5573408 | 0.80 | TDP1 (0.55) | LMNAL3MBTL1TDP1KDM4E | |
| SCHEMBL20987804 | 0.79 | LMNA (0.35) | LMNAL3MBTL1TDP1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |