Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | Q9HBH1 | 3/20 | 0.54 | |
| ▸ | MEN1 | O00255 | 11/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.51 |
| ▸ | MAPT | P10636 | 8/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.51 |
| ▸ | THRB | P10828 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | IDE | P14735 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 5/20 | 0.45 |
| ▸ | BLM | P54132 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8011193 | 1.00 | PDF (0.54) | PDFMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL8011177 | 0.89 | MEN1 (0.58) | MEN1KMT2AMAPTALDH1A1MAPK1 | |
| SCHEMBL8011171 | 0.89 | MEN1 (0.58) | MEN1KMT2AMAPTALDH1A1MAPK1 | |
| SCHEMBL29795163 | 0.75 | KDM1A (0.65) | PDFMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL31123118 | 0.75 | KDM1A (0.65) | PDFMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL343282 | 0.75 | KDM1A (0.65) | PDFMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL14556417 | 0.74 | MEN1 (0.48) | PDFMEN1KMT2AMAPTALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL5726715 | 0.73 | KDM1A (0.62) | PDFMEN1KMT2AMAPTALDH1A1 | |
| Potassium SCHEMBL30611014 | 0.73 | KDM1A (0.62) | PDFMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL18076888 | 0.73 | KDM1A (0.62) | PDFMEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000030632-A1 | ARYL AND HETEROARYL COMPOUNDS USEFUL AS FIBROBLAST GROWTH FACTOR ANTAGONISTS | EISAI CO., LTD. (JP) | 2000-06-02 | — | — | WO | claimed |
| WO-2000030632-A1 | ARYL AND HETEROARYL COMPOUNDS USEFUL AS FIBROBLAST GROWTH FACTOR ANTAGONISTS | EISAI CO., LTD. (JP) | 2000-06-02 | — | — | WO | disclosed |