SCHEMBL801119

SCHEMBL801119

CCCCc1c(-c2ccc(OCC(C)CC)c(OCC(C)CC)c2)c2cc(C)ccc2c2ccc(C)cc12

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
POLB P06746 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
MAPT P10636 1/20 0.33
HTT P42858 1/20 0.33
TLR8 Q9NR97 1/20 0.31
PDE4A P27815 1/20 0.31
PDE4B Q07343 1/20 0.31
PDE4C Q08493 1/20 0.31
PDE4D Q08499 1/20 0.31
GCGR P47871 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13044268 0.93 KDM4E (0.33) KDM4EPOLBTDP1MAPTHTT
SCHEMBL801374 0.88 TLR8 (0.36) KDM4EPOLBTDP1MAPTTLR8
SCHEMBL801378 0.85 TLR8 (0.34) KDM4EPOLBTDP1MAPTTLR8
SCHEMBL13044262 0.83 TLR8 (0.36) KDM4EPOLBTDP1MAPTTLR8
SCHEMBL14610194 0.81 TLR8 (0.38) KDM4EPOLBTDP1MAPTTLR8
SCHEMBL13044275 0.80 TLR8 (0.34) KDM4EPOLBTDP1MAPTTLR8
SCHEMBL12664828 0.76 TLR8 (0.35) KDM4EPOLBTDP1MAPTTLR8
SCHEMBL13607200 0.75 KDM4E (0.47) KDM4EPOLBTDP1MAPTTLR8
SCHEMBL5147675 0.73 TLR8 (0.45) KDM4EPOLBMAPTTLR8PDE4A
SCHEMBL13044282 0.72 DHODH (0.38) KDM4EPOLBTDP1MAPTTLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8398895-B2 Conjugated polymers and their use as organic semiconductors MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2013-03-19 US disclosed
US-8398895-B2 Conjugated polymers and their use as organic semiconductors MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2013-03-19 US disclosed
US-20120068121-A1 CONJUGATED POLYMERS AND THEIR USE AS ORGANIC SEMICONDUCTORS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2012-03-22 US disclosed
US-20120068121-A1 CONJUGATED POLYMERS AND THEIR USE AS ORGANIC SEMICONDUCTORS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2012-03-22 US disclosed
US-7947382-B2 Electroluminescent polymers and the use thereof MERCK PATENT GMBH (DE) 2011-05-24 US disclosed
US-7947382-B2 Electroluminescent polymers and the use thereof MERCK PATENT GMBH (DE) 2011-05-24 US disclosed
WO-2010136112-A1 CONJUGATED POLYMERS AND THEIR USE AS ORGANIC SEMICONDUCTORS MERCK PATENT GMBH (DE) 2010-12-02 WO disclosed
US-20070205714-A1 Electroluminescent Polymers and the Use Thereof MERCK PATENT GMBH (DE) 2007-09-06 US disclosed
US-20070205714-A1 Electroluminescent Polymers and the Use Thereof MERCK PATENT GMBH (DE) 2007-09-06 US disclosed