⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16280996 | 0.77 | KDM4E (0.42) | — | |
| SCHEMBL21293612 | 0.77 | — | — | |
| SCHEMBL7346515 | 0.76 | — | — | |
| SCHEMBL116713 | 0.76 | — | — | |
| SCHEMBL363048 | 0.74 | KMT2A (0.31) | — | |
| SCHEMBL28785644 | 0.73 | — | — | |
| SCHEMBL16208243 | 0.72 | — | — | |
| SCHEMBL27378694 | 0.72 | MCL1 (0.33) | — | |
| SCHEMBL125115 | 0.71 | — | — | |
| SCHEMBL2897138 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105814059-B | Imidazo pyrimidine derivatives as TNF active regulators | UCB生物制药私人有限公司 | 2018-04-03 | — | — | CN | disclosed |
| CN-107108554-A | It is used for the phenyl amino benzimidazole of 1 cyclohexyl 2 for treating tumour as MIDH1 inhibitor | 拜耳医药股份有限公司 | 2017-08-29 | — | — | CN | disclosed |
| CN-102695416-B | Kinase inhibitor | 金纳斯克公司 | 2017-03-08 | — | — | CN | disclosed |
| CN-104619709-B | Imidazopyridine derivatives as modulators of TNF activity | UCB生物制药私人有限公司 | 2016-11-09 | — | — | CN | disclosed |
| CN-105814059-A | Imidazopyrimidine derivatives as modulators of TNF activity | UCB生物制药私人有限公司 | 2016-07-27 | — | — | CN | disclosed |
| CN-103917590-B | Rubber combination and studless tire | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2016-06-01 | — | — | CN | disclosed |
| CN-103917589-B | Rubber composition and pneumatic tire | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2016-04-20 | — | — | CN | disclosed |
| CN-103958590-B | Rubber combination and pneumatic tyre | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2016-02-17 | — | — | CN | disclosed |
| CN-103917588-B | Rubber composition and pneumatic tire | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2016-02-17 | — | — | CN | disclosed |
| CN-103958590-A | Rubber composition and pneumatic tire | SUMITOMO RUBBER IND | 2014-07-30 | — | — | CN | disclosed |
| US-6117822-A | AS HERBICIDES AND PLANT DESICCANTS AND/OR DEFOLIANTS | BASF AKTIENGESELLSCHAFT (DE) | 2000-09-12 | — | — | US | disclosed |
| EP-0788479-B1 | SUBSTITUTED PHTHALIMIDO-CINNAMIC ACID DERIVATIVES WITH HERBICIDAL EFFECT | BASF AG (DE) | 2000-04-19 | — | — | EP | disclosed |
| US-5958837-A | 2-(PHENYLMETHOXY OR CARBONYLOXY-(1,4-PHENYLENE)-),3-HALO,5-HALOALKYLPYRIDINES; HERBICIDES EFFECTING DESICCATION AND DEFOLIATION OF PLANTS; GOOD ACTIVITY AND BETTER TAILORED CONTROL OF WEEDS | BASF AKTIENGESELLSCHAFT (DE) | 1999-09-28 | — | — | US | disclosed |
| EP-0939078-A2 | Substituted phthalimido-cinnamic acid derivatives with herbicidal activity | BASF AKTIENGESELLSCHAFT (DE) | 1999-09-01 | — | — | EP | disclosed |
| US-5885934-A | HERBICIDES OR FOR THE DESICCATION/DEFOLIATION OF PLANTS | BASF AKTIENGESELLSCHAFT (DE) | 1999-03-23 | — | — | US | disclosed |
| US-5807807-A | HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1998-09-15 | — | — | US | disclosed |
| CN-1172477-A | Substituted 2 -phenylpyridines as herbicides | BASF AG (DE) | 1998-02-04 | — | — | CN | disclosed |
| US-5707937-A | AGRICULTURAL HERBICIDES, DESICCANTS, DEFOLIANTS, HARVESTING AIDS | BASF AKTIENGESELLSCHAFT (DE) | 1998-01-13 | — | — | US | disclosed |
| EP-0788479-A1 | SUBSTITUTED PHTHALIMIDO-CINNAMIC ACID DERIVATIVES WITH HERBICIDAL EFFECT | BASF AKTIENGESELLSCHAFT (DE) | 1997-08-13 | — | — | EP | disclosed |
| WO-1996014298-A1 | SUBSTITUTED PHTHALIMIDO-CINNAMIC ACID DERIVATIVES WITH HERBICIDAL EFFECT | BASF AKTIENGESELLSCHAFT (DE) | 1996-05-17 | — | — | WO | disclosed |