Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | IDO1 | P14902 | 9/20 | 0.57 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.56 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.56 |
| ▸ | RAF1 | P04049 | 1/20 | 0.56 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.56 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.56 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.56 |
| ▸ | BRAF | P15056 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenol SCHEMBL27639361 | 0.86 | MAPT (0.81) | KDM4ECYP3A4MAPTIDO1MAPK14 | |
| SCHEMBL12491361 | 0.79 | CYP3A4 (0.64) | KDM4ECYP3A4MAPTIDO1MAPK14 | |
| SCHEMBL8119923 | 0.79 | KDM4E (0.64) | KDM4ECYP3A4MAPTIDO1MAPK14 | |
| SCHEMBL4075858 | 0.79 | KDM4E (0.64) | KDM4ECYP3A4MAPTIDO1MAPK14 | |
| SCHEMBL10992179 | 0.79 | MAPK14 (0.83) | KDM4ECYP3A4MAPTIDO1MAPK14 | |
| SCHEMBL11834419 | 0.79 | KDM4E (0.64) | KDM4ECYP3A4MAPTIDO1MAPK14 | |
| SCHEMBL224770 | 0.78 | KDM4E (1.00) | KDM4ECYP3A4MAPTIDO1MAPK14 | |
| Bromide SCHEMBL31020961 | 0.77 | KDM4E (0.96) | KDM4ECYP3A4MAPTIDO1MAPK14 | |
| SCHEMBL10989572 | 0.76 | KDM4E (0.60) | KDM4ECYP3A4MAPTIDO1MAPK14 | |
| SCHEMBL1173733 | 0.75 | MAPT (0.58) | KDM4ECYP3A4MAPTIDO1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000019994-A9 | ESTROGEN RECEPTOR LIGANDS | UNIV ILLINOIS (US) | 2000-08-31 | — | — | WO | disclosed |
| WO-2000019994-A1 | ESTROGEN RECEPTOR LIGANDS | BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2000-04-13 | — | — | WO | disclosed |