Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8375499 | 0.99 | THRA (0.45) | THRATHRBPPARALIPGPPARG | |
| SCHEMBL159096 | 0.97 | THRA (0.44) | THRATHRBPPARALIPGPPARG | |
| SCHEMBL11087732 | 0.97 | THRA (0.44) | THRATHRBPPARALIPGPPARG | |
| SCHEMBL162802 | 0.97 | THRA (0.44) | THRATHRBPPARALIPGPPARG | |
| SCHEMBL10349365 | 0.95 | THRA (0.38) | THRATHRBPPARAPPARGPTGS2 | |
| SCHEMBL11533893 | 0.94 | THRA (0.39) | THRATHRBPPARAPPARGPTGS2 | |
| SCHEMBL3967989 | 0.87 | THRA (0.48) | THRATHRBPPARALIPGPPARG | |
| SCHEMBL4405740 | 0.87 | THRA (0.48) | THRATHRBPPARALIPGPPARG | |
| SCHEMBL8600591 | 0.86 | THRA (0.47) | THRATHRBPPARALIPGPPARG | |
| SCHEMBL284750 | 0.86 | THRA (0.47) | THRATHRBPPARALIPGPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6074995-A | Triglycerides as friction modifiers in engine oil for improved fuel economy | THE LUBRIZOL CORPORATION (US) | 2000-06-13 | — | — | US | disclosed |
| EP-0573231-B1 | Triglycerides as friction modifiers in engine oil for improved fuel economy | LUBRIZOL CORP (US) | 1999-04-07 | — | — | EP | disclosed |
| EP-0471071-B1 | HIGH TEMPERATURE FUNCTIONAL FLUIDS | LUBRIZOL CORP (US) | 1995-08-30 | — | — | EP | disclosed |
| US-5366648-A | Functional fluids useful at high temperatures | THE LUBRIZOL CORPORATION (US) | 1994-11-22 | — | — | US | disclosed |
| EP-0573231-A1 | Triglycerides as friction modifiers in engine oil for improved fuel economy | The Lubrizol Corporation (US) | 1993-12-08 | — | — | EP | disclosed |
| US-5143634-A | Benzotriazole and Derivatives | AMOCO CORPORATION (US) | 1992-09-01 | — | — | US | disclosed |
| EP-0471071-A1 | HIGH TEMPERATURE FUNCTIONAL FLUIDS. | LUBRIZOL CORP (US) | 1992-02-19 | — | — | EP | disclosed |
| WO-1991013133-A2 | HIGH TEMPERATURE FUNCTIONAL FLUIDS | THE LUBRIZOL CORPORATION (US) | 1991-09-05 | — | — | WO | disclosed |
| EP-0204829-B1 | LOW PHOSPORUS- AND SULFUR-CONTAINING LUBRICATING OILS | The Lubrizol Corporation (US) | 1989-08-09 | — | — | EP | disclosed |
| EP-0221147-B1 | SULFUR-CONTAINING COMPOSITIONS, AND ADDITIVE CONCENTRATES, LUBRICATING OILS, AND METAL WORKING LUBRICANTS CONTAINING SAME | The Lubrizol Corporation (US) | 1989-06-28 | — | — | EP | disclosed |
| US-4191659-A | REACTING OLEFINIC COMPOUNDS WITH SULFUR, HYDROGEN SULFIDE IN THE PRESENCE OF A CATALYST | THE LUBRIZOL CORPORATION (US) | 1980-03-04 | — | — | US | disclosed |
| US-4171268-A | AND A SULFUR-CONTAINING EXTREME PRESSURE COMPONENT | MOONEY CHEMICALS, INC. (US) | 1979-10-16 | — | — | US | disclosed |
| US-4021419-A | Basic metal salts of sulfur- and methylene-bridged poly-phenol compositions, and epoxide-reacted derivatives thereof, and lubricants containing them | THE LUBRIZOL CORPORATION (US) | 1977-05-03 | — | — | US | disclosed |
| US-3979441-A | DISPERSANTS, VISCOSITY MODIFIERS | THE LUBRIZOL CORPORATION (US) | 1976-09-07 | — | — | US | disclosed |
| US-3953347-A | EXTREME PRESSURE ADDITIVES FOR LUBRICANTS | THE LUBRIZOL CORPORATION (US) | 1976-04-27 | — | — | US | disclosed |
| US-3951830-A | Basic metal salts of sulfur- and methylene-bridged polyphenol compositions, and epoxide-reacted derivatives thereof, and lubricants containing them | THE LUBRIZOL CORPORATION (US) | 1976-04-20 | — | — | US | disclosed |