Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10349365 | 0.99 | THRA (0.38) | THRATHRBPTGS2ALOX5PPARA | |
| SCHEMBL8375499 | 0.95 | THRA (0.45) | THRATHRBPTGS2ALOX5PPARA | |
| SCHEMBL8011394 | 0.94 | THRA (0.44) | THRATHRBPTGS2ALOX5PPARA | |
| SCHEMBL11087732 | 0.94 | THRA (0.44) | THRATHRBPTGS2ALOX5PPARA | |
| SCHEMBL159096 | 0.94 | THRA (0.44) | THRATHRBPTGS2ALOX5PPARA | |
| SCHEMBL162802 | 0.94 | THRA (0.44) | THRATHRBPTGS2ALOX5PPARA | |
| SCHEMBL4397512 | 0.87 | THRA (0.41) | THRATHRBPTGS2ALOX5PPARA | |
| SCHEMBL258595 | 0.86 | THRA (0.40) | THRATHRBPTGS2ALOX5PPARA | |
| SCHEMBL11465910 | 0.83 | L3MBTL1 (0.38) | PTGS2 | |
| SCHEMBL4405740 | 0.82 | THRA (0.48) | THRATHRBPTGS2ALOX5PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4136042-A | EXTREME PRESSURE LUBRICANTS | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1979-01-23 | — | — | US | claimed |