Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4376001 | 0.89 | POLB (0.49) | POLBSMN1; SMN2HTTNPSR1NPC1 | |
| SCHEMBL23140713 | 0.87 | POLB (0.64) | POLBHDAC8HDAC6PARP1SMN1; SMN2 | |
| SCHEMBL9145207 | 0.86 | POLB (0.48) | POLBHDAC8HDAC6PARP1SMN1; SMN2 | |
| SCHEMBL363400 | 0.85 | ALDH1A1 (0.52) | HDAC6SMN1; SMN2HTTKMT2AALDH1A1 | |
| SCHEMBL10783038 | 0.83 | POLB (0.58) | POLBHDAC8HDAC6PARP1SMN1; SMN2 | |
| SCHEMBL21636267 | 0.80 | POLB (0.62) | POLBHDAC8HDAC6PARP1SMN1; SMN2 | |
| SCHEMBL9712382 | 0.79 | RAB9A (0.48) | POLBHTTKMT2AALDH1A1NPC1 | |
| SCHEMBL910686 | 0.77 | POLB (0.47) | POLBHDAC8HDAC6PARP1SMN1; SMN2 | |
| SCHEMBL9490579 | 0.77 | MAPT (0.53) | POLBSMN1; SMN2HTTKMT2AHPGD | |
| SCHEMBL186545 | 0.76 | PARP1 (0.68) | POLBHDAC8HDAC6PARP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6096741-A | FUNGICIDES, TACHYKININ ANTAGONIST | SHIONOGI & CO., LTD. (JP) | 2000-08-01 | — | — | US | disclosed |