Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | KLK7 | P49862 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL783008 | 0.79 | MAPK1 (0.60) | MAPTHTTKLK7CA12CA1 | |
| SCHEMBL801547 | 0.79 | MAPK1 (0.60) | MAPTHTTKLK7CA12CA1 | |
| SCHEMBL801568 | 0.78 | ALDH1A1 (0.54) | MAPTCA12CA1CA2CA9 | |
| SCHEMBL783130 | 0.77 | CA12 (0.46) | MAPTHTTKLK7CA12CA1 | |
| SCHEMBL13400585 | 0.72 | EGFR (0.52) | MAPTKMT2AMAPK1LMNAMEN1 | |
| SCHEMBL801195 | 0.70 | ALDH1A1 (0.45) | MAPTHTTCA12CA1CA2 | |
| SCHEMBL22046417 | 0.70 | F3 (0.44) | MAPTHTTCA12CA1CA2 | |
| SCHEMBL28552143 | 0.69 | CA12 (0.73) | MAPTHTTKLK7CA12CA1 | |
| SCHEMBL14202628 | 0.69 | MAPT (0.66) | MAPTHTTKLK7CA12CA1 | |
| SCHEMBL13189947 | 0.69 | ALDH1A1 (0.46) | MAPTHTTCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120070856-A1 | CROSS-LINKING AGENTS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) | 2012-03-22 | — | — | US | disclosed |
| US-20120070856-A1 | CROSS-LINKING AGENTS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) | 2012-03-22 | — | — | US | disclosed |
| WO-2010100238-A1 | CROSS-LINKING AGENTS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2010-09-10 | — | — | WO | disclosed |
| EP-2226314-A1 | Cross-linking agents | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE -CNRS- (FR) | 2010-09-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120070856-A1 | CROSS-LINKING AGENTS | ORC3, TXN, PROC | MAPT 3833/4885HTT 2865/4885KLK7 3851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.