Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | PHGDH | O43175 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | CASP3 | P42574 | 2/20 | 0.39 |
| ▸ | CASP4 | P49662 | 2/20 | 0.39 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
| ▸ | CASP9 | P55211 | 2/20 | 0.39 |
| ▸ | CASP6 | P55212 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8012118 | 1.00 | SNCA (0.42) | SNCACA12CA9PHGDHCASP1 | |
| SCHEMBL8009610 | 0.87 | CA12 (0.46) | SNCACA12CA9CASP1CASP3 | |
| SCHEMBL8009607 | 0.87 | CA12 (0.46) | SNCACA12CA9CASP1CASP3 | |
| SCHEMBL8010160 | 0.86 | MEN1 (0.44) | SNCACA12CA9CASP1CASP3 | |
| SCHEMBL28408693 | 0.86 | ALDH1A1 (0.44) | SNCACA12CA9CASP1CASP3 | |
| SCHEMBL8010164 | 0.86 | MEN1 (0.44) | SNCACA12CA9CASP1CASP3 | |
| SCHEMBL4306349 | 0.85 | AKR1C3 (0.41) | MAPTSLC6A9SLC6A5NR1H2NR1H3 | |
| SCHEMBL4306346 | 0.85 | AKR1C3 (0.41) | MAPTSLC6A9SLC6A5NR1H2NR1H3 | |
| SCHEMBL4300692 | 0.84 | MAPK1 (0.48) | SNCACA12CA9KDM4EMAPT | |
| SCHEMBL4300695 | 0.84 | MAPK1 (0.48) | SNCACA12CA9KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6043254-A | ANTIPROLIFERATIVE AGENT; ENZYME INHIBITOR | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-03-28 | — | — | US | disclosed |