SCHEMBL8012277

SCHEMBL8012277

COC(=O)C(OC(=O)C(Cl)=Cc1cc(N2C(=O)C3=C(CCCC3)C2=O)c(F)cc1Cl)C1CC1

nearest known ligand 0.53

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GRM7 Q14831 1/20 0.37
GRM4 Q14833 1/20 0.37
PPOX P50336 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8012274 1.00 GRM7 (0.37) GRM7GRM4PPOX
SCHEMBL9739852 0.81 GRM7 (0.44) GRM7GRM4PPOX
SCHEMBL8002974 0.77 GRM7 (0.42) GRM7GRM4
SCHEMBL8002971 0.77 GRM7 (0.42) GRM7GRM4
SCHEMBL10569089 0.72 GRM7 (0.46) GRM7GRM4
SCHEMBL8011956 0.71 PPOX (0.40) GRM7GRM4PPOX
SCHEMBL11201432 0.70 PPOX (0.45) GRM7GRM4PPOX
SCHEMBL8089628 0.70 PPOX (0.50) GRM7GRM4PPOX
SCHEMBL10931782 0.69 PPOX (0.44) GRM7GRM4PPOX
SCHEMBL10931779 0.69 PPOX (0.44) GRM7GRM4PPOX

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6117822-A AS HERBICIDES AND PLANT DESICCANTS AND/OR DEFOLIANTS BASF AKTIENGESELLSCHAFT (DE) 2000-09-12 US disclosed
EP-0788479-B1 SUBSTITUTED PHTHALIMIDO-CINNAMIC ACID DERIVATIVES WITH HERBICIDAL EFFECT BASF AG (DE) 2000-04-19 EP disclosed
EP-0939078-A2 Substituted phthalimido-cinnamic acid derivatives with herbicidal activity BASF AKTIENGESELLSCHAFT (DE) 1999-09-01 EP disclosed
WO-1996014298-A1 SUBSTITUTED PHTHALIMIDO-CINNAMIC ACID DERIVATIVES WITH HERBICIDAL EFFECT BASF AKTIENGESELLSCHAFT (DE) 1996-05-17 WO disclosed