SCHEMBL11201432

SCHEMBL11201432

CC(C)OC(=O)c1cc(N2C(=O)C3=C(CCCC3)C2=O)c(F)cc1Cl

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PPOX P50336 1/20 0.45
GRM7 Q14831 1/20 0.44
GRM4 Q14833 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9516398 0.86 GRM7 (0.44) GRM7GRM4
SCHEMBL11207046 0.86 GRM7 (0.41) GRM7GRM4
SCHEMBL10421285 0.85 LMNA (0.39) PPOX
SCHEMBL10935535 0.85 GRM7 (0.48) GRM7GRM4
SCHEMBL9765202 0.85 PPOX (0.43) PPOXGRM7GRM4
SCHEMBL9765157 0.83 PPOX (0.40) PPOX
SCHEMBL9514181 0.83 GRM7 (0.40) GRM7GRM4
SCHEMBL29077296 0.81 GRM7 (0.47) GRM7GRM4
SCHEMBL9765563 0.81 GRM7 (0.47) GRM7GRM4
SCHEMBL9845461 0.81 PPOX (0.36) PPOXGRM7GRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0097056-A2 Herbicidal N-substituted-3,4,5,6-tetrahydrophthalamic acid derivatives NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1983-12-28 EP disclosed