Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.30 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19500080 | 0.86 | TSHR (0.32) | TSHR | |
| SCHEMBL6899774 | 0.83 | TSHR (0.39) | TSHRLMNA | |
| SCHEMBL12120687 | 0.78 | TSHR (0.34) | TSHRLMNA | |
| SCHEMBL22735042 | 0.77 | HTT (0.50) | TSHRLMNAHSD17B10 | |
| SCHEMBL22372416 | 0.76 | TSHR (0.33) | TSHRLMNA | |
| SCHEMBL28325238 | 0.76 | ALDH1A1 (0.38) | TSHRLMNAHSD17B10GRIN2DGRIN3B | |
| SCHEMBL19236580 | 0.75 | TSHR (0.32) | TSHR | |
| SCHEMBL6900393 | 0.75 | LMNA (0.39) | TSHRLMNAHSD17B10 | |
| SCHEMBL22345976 | 0.74 | HTT (0.37) | TSHRLMNAHSD17B10GRIN2DGRIN3B | |
| SCHEMBL22735024 | 0.73 | TSHR (0.34) | TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0830336-A4 | PROCESS FOR THE PREPARATION OF TERTIARY AMINOCARBONATES AND AMINOETHERS | OSI SPECIALTIES INC (US) | 2000-04-05 | — | — | EP | disclosed |
| EP-0830336-A1 | PROCESS FOR THE PREPARATION OF TERTIARY AMINOCARBONATES AND AMINOETHERS | OSi Specialties, Inc. (US) | 1998-03-25 | — | — | EP | disclosed |
| WO-1996040613-A1 | PROCESS FOR THE PREPARATION OF TERTIARY AMINOCARBONATES AND AMINOETHERS | OSI SPECIALTIES, INC. (US) | 1996-12-19 | — | — | WO | disclosed |