Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 8/20 | 0.51 |
| ▸ | MMP1 | P03956 | 2/20 | 0.51 |
| ▸ | MMP8 | P22894 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8003278 | 0.91 | BMP1 (0.52) | BMP1MMP1MMP8ALDH1A1TSHR | |
| SCHEMBL8003538 | 0.90 | BMP1 (0.51) | BMP1MMP1MMP8TSHRSMN1; SMN2 | |
| SCHEMBL8015007 | 0.89 | BMP1 (0.52) | BMP1MMP1MMP8ALDH1A1TSHR | |
| SCHEMBL8013077 | 0.88 | BMP1 (0.55) | BMP1MMP1MMP8ALDH1A1TSHR | |
| SCHEMBL8012949 | 0.87 | BMP1 (0.52) | BMP1MMP1MMP8ALDH1A1TSHR | |
| SCHEMBL8014664 | 0.87 | BMP1 (0.55) | BMP1MMP1MMP8ALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL8015082 | 0.86 | BMP1 (0.49) | BMP1MMP1MMP8 | |
| SCHEMBL8012143 | 0.86 | MMP2 (0.54) | BMP1MMP1MMP8ALDH1A1TSHR | |
| SCHEMBL8012387 | 0.85 | BMP1 (0.57) | BMP1MMP1MMP8ALDH1A1TSHR | |
| SCHEMBL8011724 | 0.85 | BMP1 (0.53) | BMP1MMP1MMP8ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6153609-A | Arylsulfonylamino hydroxamic acid derivatives | PFIZER INC (US) | 2000-11-28 | — | — | US | disclosed |
| EP-0922030-A1 | ARYLSULFONYLAMINO HYDROXAMIC ACID DERIVATIVES | PFIZER INC. (US) | 1999-06-16 | — | — | EP | disclosed |
| WO-1998007697-A1 | ARYLSULFONYLAMINO HYDROXAMIC ACID DERIVATIVES | PFIZER INC. (US) | 1998-02-26 | — | — | WO | disclosed |